A functional role for CCR6 on proallergic T cells in the gastrointestinal tract (Q24655787)

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Adina Kay Knight

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Hoheteberhan Getachew

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Jonathan S Bromberg

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Sergio A Lira

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Lloyd Mayer

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M Cecilia Berin

Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans

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language of work or name

English

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publication date

January 2010

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published in

Gastroenterology

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volume

138

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issue

1

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page(s)

275-84.e1-4

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cites work

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CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells

7 April 2017

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IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.

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CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles

28 September 2017

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CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches.

28 September 2017

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Gut-associated lymphoid tissue-primed CD4+ T cells display CCR9-dependent and -independent homing to the small intestine.

28 September 2017

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Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo

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Novel markers of the human follicle-associated epithelium identified by genomic profiling and microdissection

28 September 2017

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Absence of CCR6 inhibits CD4+ regulatory T-cell development and M-cell formation inside Peyer's patches

28 September 2017

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A distinct subset of chemokines dominates the mucosal chemokine response in inflammatory bowel disease.

28 September 2017

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Mast cells are required for experimental oral allergen-induced diarrhea

28 September 2017

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T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase.

28 September 2017

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Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function

28 September 2017

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Local allergic reaction in food-hypersensitive adults despite a lack of systemic food-specific IgE.

28 September 2017

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CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses

28 September 2017

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CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue.

28 September 2017

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Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine

28 September 2017

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FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homin

28 September 2017

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Role of mast cells in ion transport abnormalities associated with intestinal anaphylaxis. Correction of the diminished secretory response in genetically mast cell-deficient W/Wv mice by bone marrow transplantation

28 September 2017

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Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea

28 September 2017

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Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells

30 May 2018

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Regulatory role of Peyer's patches for the inhibition of OVA-induced allergic diarrhea.

30 May 2018

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FTY720 suppresses CD4+CD44highCD62L- effector memory T cell-mediated colitis.

28 November 2018

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Attenuation of allergen-induced responses in CCR6-/- mice is dependent upon altered pulmonary T lymphocyte activation.

28 November 2018

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Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells

28 November 2018

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Therapeutic effects of a new lymphocyte homing reagent FTY720 in interleukin-10 gene-deficient mice with colitis

28 November 2018

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CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720.

28 November 2018

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Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity

28 November 2018

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Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis.

28 November 2018

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Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine

28 November 2018

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Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile

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Lymphoid precursors in intestinal cryptopatches express CCR6 and undergo dysregulated development in the absence of CCR6

1 reference

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The influence of mast cells on pathways of transepithelial antigen transport in rat intestine

1 reference

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FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing

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Sphingosine 1-phosphate-mediated trafficking of pathogenic Th2 and mast cells for the control of food allergy

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CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice

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Characterization of enteric functional changes evoked by in vivo anti-CD3 T cell activation

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