A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9 (Q24656693)

Europe PubMed Central

title

A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9 (English)

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author name string

Geraldine M O'Neill

1

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Sachiko Seo

2

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Ilya G Serebriiskii

3

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Stuart R Lessin

4

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Erica A Golemis

HEF1-dependent Aurora A activation induces disassembly of the primary cilium

5

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language of work or name

English

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publication date

1 October 2007

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published in

Cancer Research

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volume

67

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issue

19

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page(s)

8975-9

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cites work

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Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes

7 April 2017

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Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae

7 April 2017

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Tensional homeostasis and the malignant phenotype

7 April 2017

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Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle

7 April 2017

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Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia

7 April 2017

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The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking

7 April 2017

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Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7

7 April 2017

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HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

7 April 2017

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Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: possible involvement of Nedd9 in the differentiation of neurons after ischemia

7 April 2017

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The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

7 April 2017

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Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance

7 April 2017

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Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion

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BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl

7 April 2017

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Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

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Genes that mediate breast cancer metastasis to lung

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

7 April 2017

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7 April 2017

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Structure and function of cas-L and integrin-mediated signaling

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Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle

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The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42.

28 September 2017

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28 September 2017

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Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene

28 November 2018

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Dissection of HEF1-dependent functions in motility and transcriptional regulation

28 November 2018

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10.1158/0008-5472.CAN-07-1328

28 November 2018

Identifiers

DOI

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PubMed publication ID

17908996

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