RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells (Q24657337)

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M L Deftos

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E W Ojala

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M J Bevan

Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells

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language of work or name

English

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publication date

December 1998

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published in

Immunity

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volume

9

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issue

6

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page(s)

797-806

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cites work

1 reference

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Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

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RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

7 April 2017

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Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

7 April 2017

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ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle

7 April 2017

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Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

7 April 2017

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Genomic structure and chromosomal mapping of the nuclear orphan receptor ROR gamma (RORC) gene

7 April 2017

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Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element

7 April 2017

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A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death

7 April 2017

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TOR: a new orphan receptor expressed in the thymus that can modulate retinoid and thyroid hormone signals

7 April 2017

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Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors

7 April 2017

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A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death

7 April 2017

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The RXR heterodimers and orphan receptors

7 April 2017

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Steroid hormone receptors: many actors in search of a plot

7 April 2017

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7 April 2017

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Correlating notch signaling with thymocyte maturation

7 April 2017

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Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression

28 September 2017

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Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells

28 September 2017

1 reference

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Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway

28 September 2017

1 reference

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Applications of retrovirus-mediated expression cloning

28 September 2017

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Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells

28 September 2017

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Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

28 September 2017

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Molecular basis for developmental changes in interleukin-2 gene inducibility

28 September 2017

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Programmed cell death and the control of cell survival: lessons from the nervous system

28 September 2017

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

28 September 2017

1 reference

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Development and selection of T cells: facts and puzzles

28 September 2017

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The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

An essential role for gp39, the ligand for CD40, in thymic selection.

28 September 2017

1 reference

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Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Helper signals in the plaque-forming cell response to protein-bound haptens

28 September 2017

1 reference

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Identification of the DNA binding site for NGFI-B by genetic selection in yeast

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Retinoids are important cofactors in T cell activation

28 September 2017

1 reference

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Glucocorticoid-induced apoptosis in the thymus

28 September 2017

1 reference

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Induction of apoptosis in mature T cells by tumour necrosis factor

28 September 2017

1 reference

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Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

A role for Fas in negative selection of thymocytes in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Fas ligand mediates activation-induced cell death in human T lymphocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Expression and function of mouse Fas antigen on immature and mature T cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776668

The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult alpha beta thymocytes

28 November 2018

1 reference

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