The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism (Q24657371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380679%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism (English)

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7 November 2019

5

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7 November 2019

author name string

B M Forman

1

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7 November 2019

B Ruan

2

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7 November 2019

J Chen

3

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7 November 2019

G J Schroepfer

4

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7 November 2019

language of work or name

English

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publication date

1 September 1997

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7 November 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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7 November 2019

volume

94

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7 November 2019

page(s)

10588-10593

1 reference

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7 November 2019

issue

20

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

7 November 2019

cites work

1 reference

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

7 April 2017

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

7 April 2017

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Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors

7 April 2017

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A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily

7 April 2017

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NER, a new member of the gene family encoding the human steroid hormone nuclear receptor

7 April 2017

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OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor

7 April 2017

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LXR, a nuclear receptor that defines a distinct retinoid response pathway

7 April 2017

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7 April 2017

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Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart.

7 April 2017

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

7 April 2017

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

7 April 2017

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Identification of a nuclear receptor that is activated by farnesol metabolites

7 April 2017

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Unique response pathways are established by allosteric interactions among nuclear hormone receptors

7 April 2017

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Cholesterol side-chain cleavage by mitochondria from the human placenta. Studies using hydroxycholesterols as substrates

7 April 2017

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Studies on steroids. Part 37. Synthesis of the four stereoisomers of 20,22-epoxycholesterol

7 April 2017

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The RXR heterodimers and orphan receptors

7 April 2017

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Regulation of the mevalonate pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23411

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

7 April 2017

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

7 April 2017

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Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: application to the enzymatic formation of cholesta-5,8-dien-3 beta-ol

7 April 2017

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RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo

28 September 2017

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Protein prenylation in eukaryotic microorganisms: genetics, biology and biochemistry

28 September 2017

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Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

28 September 2017

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Identification of the DNA binding site for NGFI-B by genetic selection in yeast

28 September 2017

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Sequence dependence of protein isoprenylation

28 September 2017

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Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.

28 September 2017

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Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells

28 September 2017

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Suppression of the proliferation of Ras-transformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism.

28 September 2017

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28 September 2017

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Correlation among oxysterol potencies in the regulation of the degradation of 3-hydroxy-3-methylglutaryl CoA reductase, the repression of 3-hydroxy-3-methylglutaryl CoA synthase and affinities for the oxysterol receptor

30 May 2018

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Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct

30 May 2018

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30 May 2018

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28 November 2018

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12 December 2020

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12 December 2020

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Stereospecific synthesis of the four 20,22-epoxycholesterols and of (Z)-20(22)-dehydrocholesterol

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.20.10588

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1073/PNAS.94.20.10588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380679%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380679%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference