A molecular link between the active component of marijuana and Alzheimer's disease pathology (Q24657485)

1

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Claude J Rogers

2

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Albert E Beuscher

3

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Arthur J Olson

5

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Tobin J Dickerson

6

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Kim D Janda

7

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language of work or name

English

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publication date

2006

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Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains

published in

Molecular Pharmaceutics

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volume

3

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page(s)

773-7

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issue

6

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cites work

1 reference

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A new and rapid colorimetric determination of acetylcholinesterase activity

7 April 2017

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International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

7 April 2017

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Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation

7 April 2017

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The peripheral anionic site of acetylcholinesterase: structure, functions and potential role in rational drug design

28 September 2017

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A credit-card library approach for disrupting protein-protein interactions

28 September 2017

1 reference

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Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library

28 September 2017

1 reference

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Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

28 September 2017

1 reference

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Role of the endocannabinoid system in Alzheimer's disease: new perspectives.

28 September 2017

1 reference

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Acetylcholinesterase inhibitors: novel activities of old molecules.

28 September 2017

1 reference

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The good and the bad effects of (-) trans-delta-9-tetrahydrocannabinol (Delta 9-THC) on humans

28 September 2017

1 reference

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Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease

28 September 2017

1 reference

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Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide.

28 September 2017

1 reference

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Estimated prevalence of Alzheimer's disease in the United States

28 September 2017

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Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.

28 September 2017

1 reference

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Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.

30 May 2018

1 reference

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

30 May 2018

1 reference

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A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition.

30 May 2018

1 reference

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Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation

30 May 2018

1 reference

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Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells

28 November 2018

1 reference

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3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy

28 November 2018

1 reference

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beta-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies

28 November 2018

1 reference

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Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562334

Is senile dementia "age-related" or "ageing-related"?--evidence from meta-analysis of dementia prevalence in the oldest old

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17140265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular rotors as fluorescent probes for biological studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17140265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/17140265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/MP060066M

1 reference

418926

418926

1 reference

1 reference

1 reference