High-resolution structures of bacterially expressed soluble human CD59 (Q24657819)

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3 January 2020

title

High-resolution structures of bacterially expressed soluble human CD59 (English)

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3 January 2020

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condensed matter physics

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author

Pietro Roversi

3

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3 January 2020

Steven Johnson

2

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3 January 2020

Bryan Paul Morgan

7

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3 January 2020

Susan M. Lea

8

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3 January 2020

author name string

Kirstin J Leath

1

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3 January 2020

Timothy R Hughes

4

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3 January 2020

Richard A G Smith

5

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3 January 2020

Lloyd Mackenzie

6

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language of work or name

English

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publication date

28 July 2007

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Acta Crystallographica Section F: Structural Biology Communications

3 January 2020

published in

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3 January 2020

volume

63

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3 January 2020

issue

Pt 8

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3 January 2020

page(s)

648-652

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THESEUS: maximum likelihood superpositioning and analysis of macromolecular structures

3 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Structure of a soluble, glycosylated form of the human complement regulatory protein CD59

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Likelihood-enhanced fast translation functions

7 April 2017

1 reference

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Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT

7 April 2017

1 reference

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Coot: model-building tools for molecular graphics

7 April 2017

1 reference

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The CCP4 suite: programs for protein crystallography

7 April 2017

1 reference

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ARP/wARP and automatic interpretation of protein electron density maps

7 April 2017

1 reference

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Defining the CD59-C9 binding interaction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

The human complement regulatory protein CD59 binds to the alpha-chain of C8 and to the "b"domain of C9

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Protection of erythrocytes from human complement-mediated lysis by membrane-targeted recombinant soluble CD59: a new approach to PNH therapy

7 April 2017

1 reference

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Complement function in mAb-mediated cancer immunotherapy

28 September 2017

1 reference

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Complement therapeutics; history and current progress.

28 September 2017

1 reference

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Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors

28 September 2017

1 reference

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CD59 blocks not only the insertion of C9 into MAC but inhibits ion channel formation by homologous C5b-8 as well as C5b-9.

28 September 2017

1 reference

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CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma.

28 September 2017

1 reference

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Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335151

Insights into the human CD59 complement binding interface toward engineering new therapeutics

30 May 2018

1 reference

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Expression of complement regulatory proteins-CD 35, CD 46, CD 55, and CD 59-in benign and malignant endometrial tissue

28 November 2018

1 reference

12 December 2020

A synthetic peptide from complement protein C9 binds to CD59 and enhances lysis of human erythrocytes by C5b-9

1 reference

12 December 2020

A study of human DAF, CD59, MCP transgene in xenotransplantation

1 reference

12 December 2020

Structure-function relationships of the complement regulatory protein, CD59

1 reference

12 December 2020

10.1107/S1744309107033477

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17671359%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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3 January 2020

PubMed publication ID

17671359

1 reference