Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin (Q24670040)

1

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Eero Lehtonen

2

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Krystyna Kudlicka

3

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Harry Holthöfer

The American Journal of Pathology

4

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language of work or name

English

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publication date

September 2004

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published in

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volume

165

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issue

3

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page(s)

923-36

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cites work

Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

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A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia

7 April 2017

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Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

7 April 2017

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Regulation of cadherin adhesive activity

7 April 2017

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Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion

7 April 2017

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Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins

7 April 2017

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Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney

7 April 2017

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Nephrin is specifically located at the slit diaphragm of glomerular podocytes

7 April 2017

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Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes

7 April 2017

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Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

7 April 2017

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Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells

7 April 2017

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Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

7 April 2017

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Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1

7 April 2017

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The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1

7 April 2017

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N-linked glycosylation is critical for the plasma membrane localization of nephrin

7 April 2017

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Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex

7 April 2017

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Interaction with podocin facilitates nephrin signaling

7 April 2017

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Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells

7 April 2017

1 reference

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In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins

7 April 2017

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The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex

7 April 2017

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Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes

7 April 2017

1 reference

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Podocyte slit-diaphragm protein nephrin is linked to the actin cytoskeleton

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

The glomerular epithelial cell anti-adhesin podocalyxin associates with the actin cytoskeleton through interactions with ezrin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Expression of podocalyxin inhibits cell-cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Cadherin cell adhesion receptors as a morphogenetic regulator

7 April 2017

1 reference

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Glomerular permeability. II. Ferritin transfer across the glomerular capillary wall in nephrotic rats

7 April 2017

1 reference

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A novel protein, densin, expressed by glomerular podocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Genetic studies define MAGUK proteins as regulators of epithelial cell polarity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Interaction of endogenous nephrin and CD2-associated protein in mouse epithelial M-1 cell line

28 September 2017

1 reference

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Use of mass spectrometry to study signaling pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Nephritogenic mAb 5-1-6 is directed at the extracellular domain of rat nephrin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Structural and signalling molecules come together at tight junctions

28 September 2017

1 reference

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Cloning and expression of the rat nephrin homolog.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Precocious mammary gland development in P-cadherin-deficient mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Diversity among tight junctions in rat kidney: glomerular slit diaphragms and endothelial junctions express only one isoform of the tight junction protein ZO-1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Localization of GTPases by indirect immunofluorescence and immunoelectron microscopy

28 September 2017

1 reference

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A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Role of nephrin in cell junction formation in human nephrogenesis

28 September 2017

1 reference

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Correlation between IL-3 receptor expression and growth potential of human CD34+ hematopoietic cells from different tissues

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Nephrin localizes to the slit pore of the glomerular epithelial cell

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Regulation of the movement of solutes across tight junctions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Differentiation of epithelial foot processes and filtration slits: sequential appearance of occluding junctions, epithelial polyanion, and slit membranes in developing glomeruli

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

CD2-associated protein directly interacts with the actin cytoskeleton.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Determinants of vascular permeability in the kidney glomerulus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

CASK and protein 4.1 support F-actin nucleation on neurexins

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

The p120 catenin family: complex roles in adhesion, signaling and cancer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Congenital nephrotic syndrome in mice lacking CD2-associated protein

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

Biosynthesis of the gp330/44-kDa Heymann nephritis antigenic complex: assembly takes place in the ER.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618613

FAT is a component of glomerular slit diaphragms

28 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963354-8

Nephrin TRAP Mice Lack Slit Diaphragms and Show Fibrotic Glomeruli and Cystic Tubular Lesions

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963354-8

The glomerular slit diaphragm is a modified adherens junction

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15331416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alterations of the glomerular epithelium in acute aminonucleoside nephrosis. Evidence for formation of occluding junctions and epithelial cell detachment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15331416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)63354-8

1 reference

1 reference

1 reference

PubMed publication ID

15331416

1 reference