Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma (Q24670483)

2

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Mary Crainie

3

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Michael J Mant

4

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Andrew R Belch

5

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Linda M Pilarski

RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability

6

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language of work or name

English

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publication date

15 June 2005

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published in

Blood

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volume

105

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issue

12

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page(s)

4836-44

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cites work

1 reference

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Expression of human hyaluronan synthases in response to external stimuli

7 April 2017

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Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity

7 April 2017

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Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group

7 April 2017

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Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells

7 April 2017

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Overexpression of the receptor for hyaluronan-mediated motility (RHAMM) characterizes the malignant clone in multiple myeloma: identification of three distinct RHAMM variants

7 April 2017

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Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

7 April 2017

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AU-rich elements: characterization and importance in mRNA degradation

7 April 2017

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The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: causes and consequences

7 April 2017

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Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.

7 April 2017

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Abnormal expression of hyaluronan synthases in patients with Waldenstrom's macroglobulimenia

28 September 2017

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Post-transcriptional regulation of gene expression by degradation of messenger RNAs

28 September 2017

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Alternative and aberrant splicing of MDM2 mRNA in human cancer

28 September 2017

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Alternative spliced transcripts as cancer markers

28 September 2017

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Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer

28 September 2017

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Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells

28 September 2017

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Rapid hyaluronan uptake is associated with enhanced motility: implications for an intracellular mode of action

28 September 2017

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Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

28 September 2017

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Unusual alternative splicing within the human kallikrein genes KLK2 and KLK3 gives rise to novel prostate-specific proteins

28 September 2017

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Three novel types of splicing aberrations in the tuberous sclerosis TSC2 gene caused by mutations apart from splice consensus sequences.

30 May 2018

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Intracellular localization of hyaluronan in proliferating cells

30 May 2018

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Reported in vivo splice-site mutations in the factor IX gene: severity of splicing defects and a hypothesis for predicting deleterious splice donor mutations

30 May 2018

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Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

30 May 2018

1 reference

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Ras-transformed cells express both CD44 and RHAMM hyaluronan receptors: only RHAMM is essential for hyaluronan-promoted locomotion

30 May 2018

1 reference

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Assembly of a chondrocyte-like pericellular matrix on non-chondrogenic cells. Role of the cell surface hyaluronan receptors in the assembly of a pericellular matrix

30 May 2018

1 reference

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Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients

30 May 2018

1 reference

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Glucocorticoids inhibit induced and non-induced mRNA accumulation of genes encoding hyaluronan synthases (HAS): hydrocortisone inhibits HAS1 activation by blocking the p38 mitogen-activated protein kinase signalling pathway

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894997

Endoplasmic reticulum stress induces hyaluronan deposition and leukocyte adhesion

28 November 2018

1 reference

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Regulation of Multidrug Resistance in Cancer Cells by Hyaluronan

28 November 2018

1 reference

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In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894997

A high frequency of circulating B cells share clonotypic Ig heavy-chain VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single-cell and in situ reverse transcriptase-polymerase chain reaction.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894997

Deficient drug transporter function of bone marrow-localized and leukemic plasma cells in multiple myeloma

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894997

CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894997

The impact of extracellular matrix on chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy

28 November 2018

1 reference

12 December 2020

Serum hyaluronan in patients with multiple myeloma: correlation with survival and Ig concentration

1 reference

12 December 2020

An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2

1 reference

12 December 2020

Interaction of CD44 with Different Forms of Hyaluronic Acid. Its Role in Adhesion and Migration of Tumor Cells

1 reference

12 December 2020

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

1 reference

12 December 2020

Expression and function of a receptor for hyaluronan-mediated motility on normal and malignant B lymphocytes

1 reference

12 December 2020

The blood B-cells and bone marrow plasma cells in patients with multiple myeloma share identical IgH rearrangements

1 reference

12 December 2020

Hyaluronan-dependent motility of B cells and leukemic plasma cells in blood, but not of bone marrow plasma cells, in multiple myeloma: alternate use of receptor for hyaluronan-mediated motility (RHAMM) and CD44

1 reference

12 December 2020

Expression of hyaluronan in benign and malignant breast lesions

1 reference

12 December 2020

The impact of extracellular matrix on the chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy.

1 reference

Crossref

https://api.crossref.org/works/10.1182%2FBLOOD-2004-10-3825

7 January 2021