Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta (Q24670614)

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English	Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta	scientific article

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28 December 2019

Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta (English)

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28 December 2019

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28 December 2019

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Nadine Stahmann

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28 December 2019

Angela Woods

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28 December 2019

Regine Heller

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1 August 2006

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28 December 2019

Molecular and Cellular Biology

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28 December 2019

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28 December 2019

5933-5945

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28 December 2019

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28 December 2019

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

1 reference

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7 April 2017

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

1 reference

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7 April 2017

Role of AMP-activated protein kinase in mechanism of metformin action

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Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

1 reference

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7 April 2017

The AMP-activated protein kinase cascade--a unifying system for energy control

1 reference

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7 April 2017

Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro

1 reference

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7 April 2017

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

1 reference

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7 April 2017

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

1 reference

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The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro

1 reference

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

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Protease-activated receptors in hemostasis, thrombosis and vascular biology

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28 September 2017

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

1 reference

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28 September 2017

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

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28 September 2017

AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle

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AMP-activated protein kinase: a master switch in glucose and lipid metabolism.

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Role of thrombin in angiogenesis and tumor progression

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Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

1 reference

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Thrombin and Phenotypic Modulation of the Endothelium

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28 September 2017

Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

1 reference

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Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase

1 reference

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28 September 2017

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

1 reference

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STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase

1 reference

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28 September 2017

Molecular mechanisms of thrombin-induced endothelial cell permeability

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28 September 2017

Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.

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28 September 2017

Regulation of endothelial cell barrier function by calcium/calmodulin-dependent protein kinase II.

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L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin

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Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1.

1 reference

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28 September 2017

AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592798

28 September 2017

Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay

1 reference

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30 May 2018

Estradiol-mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase.

1 reference

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28 November 2018

Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177.

1 reference

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Hypoxic modulation of Ca2+ signaling in human venous endothelial cells. Multiple roles for reactive oxygen species

1 reference

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28 November 2018

AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592798

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Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt

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Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592798

28 November 2018

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592798

28 November 2018

Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592798

28 November 2018

Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

1 reference

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28 November 2018

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592798

28 November 2018

Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.

1 reference

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28 November 2018

Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation

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28 November 2018

The Effect of AMP-Activated Protein Kinase and Its Activator AICAR on the Metabolism of Human Umbilical Vein Endothelial Cells

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28 November 2018

AMP-Activated protein kinase is activated by the stimulations of G(q)-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Gαq and phospholipase C‐β2 in human platelets activation by thrombin receptors PAR1 and PAR4: studies in human platelets deficient in Gαq and phospholipase C‐β2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase phosphorylation of endothelial NO synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II-stimulated induction of sis-inducing factor is mediated by pertussis toxin-insensitive G(q) proteins in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16880506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00383-06

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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28 December 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16880506%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16880506%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

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