Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium (Q24671018)

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Tatyana Matrosovich

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Michaela Beyerle

3

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Wolfgang Garten

5

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Mikhail Matrosovich

The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells

6

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language of work or name

English

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publication date

October 2006

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published in

Journal of Virology

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volume

80

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issue

19

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page(s)

9896-8

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cites work

1 reference

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Cloning and characterization of the cDNA for human airway trypsin-like protease

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Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3

7 April 2017

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Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway

7 April 2017

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Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer

7 April 2017

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Localization of human airway trypsin-like protease in the airway: an immunohistochemical study

7 April 2017

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7 April 2017

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Purification, characterization, and localization of a novel trypsin-like protease found in the human airway

7 April 2017

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Human and avian influenza viruses target different cell types in cultures of human airway epithelium.

7 April 2017

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Human Airway Trypsin-Like Protease Increases Mucin Gene Expression in Airway Epithelial Cells

28 September 2017

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Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors

28 September 2017

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Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases

28 September 2017

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Regulation of the epithelial sodium channel by serine proteases in human airways

28 September 2017

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Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

28 September 2017

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Mast cell tryptase from pig lungs triggers infection by pneumotropic Sendai and influenza A viruses. Purification and characterization

28 September 2017

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Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

28 September 2017

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Role of hemagglutinin cleavage for the pathogenicity of influenza virus.

28 September 2017

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Host cell proteases controlling virus pathogenicity

28 September 2017

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28 September 2017

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Activation of influenza A viruses by trypsin treatment

28 September 2017

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Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide

28 September 2017

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Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

28 September 2017

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Cell tropism of influenza virus mediated by hemagglutinin activation at the stage of virus entry

28 September 2017

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Identification of ectopic anionic trypsin I in rat lungs potentiating pneumotropic virus infectivity and increased enzyme level after virus infection

30 May 2018

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Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virus

28 November 2018

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Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16973594

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar epithelial Clara cells. A possible activator of the viral fusion glycoprotein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16973594