Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay (Q24671869)

7

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Emily Flashman

object named as

Emily Flashman

2

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Peter J. Ratcliffe

object named as

Peter J Ratcliffe

6

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Kirsty S Hewitson

5

object named as

Kirsty S Hewitson

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author name string

Dominic Ehrismann

1

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David N Genn

3

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Nicolas Mathioudakis

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

4

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language of work or name

English

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publication date

1 January 2007

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published in

Biochemical Journal

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volume

401

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page(s)

227-34

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issue

1

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cites work

1 reference

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

7 April 2017

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Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803

7 April 2017

1 reference

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The use of dioxygen by HIF prolyl hydroxylase (PHD1)

7 April 2017

1 reference

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Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

7 April 2017

1 reference

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Assessment of tissue oxygen tension: comparison of dynamic fluorescence quenching and polarographic electrode technique

7 April 2017

1 reference

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

7 April 2017

1 reference

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A conserved family of prolyl-4-hydroxylases that modify HIF

7 April 2017

1 reference

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

7 April 2017

1 reference

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Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease

7 April 2017

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

7 April 2017

1 reference

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Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source

7 April 2017

1 reference

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

7 April 2017

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

7 April 2017

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Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

7 April 2017

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

7 April 2017

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

7 April 2017

1 reference

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Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

7 April 2017

1 reference

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

7 April 2017

1 reference

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Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate

7 April 2017

1 reference

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Hydroxylation of HIF-1: oxygen sensing at the molecular level

7 April 2017

1 reference

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Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells

7 April 2017

1 reference

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

7 April 2017

1 reference

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Characterization of alpha-ketoglutarate-dependent taurine dioxygenase from Escherichia coli

7 April 2017

1 reference

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

7 April 2017

1 reference

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Purification and characterization of hypoxia-inducible factor 1

7 April 2017

1 reference

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Oxygen sensing by HIF hydroxylases

7 April 2017

1 reference

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Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia.

7 April 2017

1 reference

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Dioxygenases as O2-dependent regulators of the hypoxic response pathway

28 September 2017

1 reference

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Signalling hypoxia by HIF hydroxylases

28 September 2017

1 reference

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Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha

28 September 2017

1 reference

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Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

28 September 2017

1 reference

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Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors

28 September 2017

1 reference

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Determination and comparison of specific activity of the HIF-prolyl hydroxylases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698668

Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit

28 September 2017

1 reference

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Effect of periodate oxidation on the structure and properties of glucose oxidase

28 September 2017

1 reference

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Incorporation of oxygen into the succinate co-product of iron(II) and 2-oxoglutarate dependent oxygenases from bacteria, plants and humans

28 September 2017

1 reference

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Studies on the specificity of unprocessed and mature forms of phytanoyl-CoA 2-hydroxylase and mutation of the iron binding ligands

28 November 2018

1 reference

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A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases

28 November 2018

1 reference

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

28 November 2018

1 reference

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Pericellular PO2 and O2 consumption in monolayer cell cultures.

28 November 2018

1 reference

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Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

28 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/16952279