Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay (Q24672180)

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English	Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay	scientific article

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scholarly article

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Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay (English)

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1 reference

ChEBI release 2020-05-28

author name string

H-J Behrendt

1

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T Germann

2

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C Gillen

3

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H Hatt

4

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R Jostock

5

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language of work or name

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publication date

February 2004

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British Journal of Pharmacology

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141

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4

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737-45

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Neurogenic responses mediated by vanilloid receptor-1 (TRPV1) are blocked by the high affinity antagonist, iodo-resiniferatoxin

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An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

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N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

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Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture

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ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

1 reference

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Menthol: a natural analgesic compound

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7 April 2017

A TRP channel that senses cold stimuli and menthol

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7 April 2017

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

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Characterisation of a human acid-sensing ion channel (hASIC1a) endogenously expressed in HEK293 cells

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7 April 2017

Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology

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Impaired nociception and pain sensation in mice lacking the capsaicin receptor

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The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

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Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

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Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia

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7 April 2017

The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin

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7 April 2017

The cloned capsaicin receptor integrates multiple pain-producing stimuli

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7 April 2017

ThermoTRP channels and beyond: mechanisms of temperature sensation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

28 September 2017

Low pH potentiates both capsaicin binding and channel gating of VR1 receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

28 September 2017

N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflammatory and neu

1 reference

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Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: roles in regulation of cardiovascular function.

1 reference

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Voltage-dependent block of neuronal and skeletal muscle sodium channels by thymol and menthol

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A novel treatment of postherpetic neuralgia using peppermint oil.

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Anandamide: some like it hot.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

28 September 2017

Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

28 September 2017

Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

28 September 2017

Measurement of [Ca2+] using the Fluorometric Imaging Plate Reader (FLIPR).

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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Menthol and related cooling compounds

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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AG-3–5: a chemical producing sensations of cold

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1.

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30 May 2018

Pharmacological characterization of the vanilloid receptor in the rat dorsal spinal cord.

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30 May 2018

N-(4-Tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: I. In Vitro Characterization and Pharmacokinetic Properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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TRPM8 mRNA is expressed in a subset of cold-responsive trigeminal neurons from rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

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(-)-Linalool produces antinociception in two experimental models of pain.

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A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574235

28 November 2018

Ion channels activated by cold and menthol in cultured rat dorsal root ganglion neurones.

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28 November 2018

A unified nomenclature for the superfamily of TRP cation channels.

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Molecular basis for species-specific sensitivity to "hot" chili peppers

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Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties.

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Pharmacological aspects of shaking behavior produced by TRH, AG-3-5, and morphine withdrawal

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of menthol on two types of Ca currents in cultured sensory neurons of vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/14757700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Menthol desensitization of capsaicin irritation. Evidence of a short-term anti-nociceptive effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/14757700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0705652

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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