Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor (Q24672186)

1

Dirk M Zajonc

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Luc Teyton

8

Luc Teyton

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Carlos Cantu-Brito

2

Carlos Cantu

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Jochen Mattner

3

Jochen Mattner

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Dapeng Zhou

4

Dapeng Zhou

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Albert Bendelac

6

Albert Bendelac

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author name string

Paul B Savage

Molecular mechanism of lipopeptide presentation by CD1a

5

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language of work or name

English

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publication date

August 2005

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published in

Nature Immunology

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volume

6

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issue

8

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page(s)

810-8

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cites work

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The crystal structure of human CD1b with a bound bacterial glycolipid

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Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A

7 April 2017

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Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains

7 April 2017

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Electrostatics of nanosystems: application to microtubules and the ribosome

7 April 2017

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Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

7 April 2017

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Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors

7 April 2017

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The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity

7 April 2017

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Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes

7 April 2017

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Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove

7 April 2017

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Raster3D: photorealistic molecular graphics

7 April 2017

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7 April 2017

Refinement of macromolecular structures by the maximum-likelihood method

22 April 2017

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The CCP4 suite: programs for protein crystallography

7 April 2017

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

7 April 2017

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Structure validation by Calpha geometry: phi,psi and Cbeta deviation

7 April 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

7 April 2017

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Autoreactivity by design: innate B and T lymphocytes

7 April 2017

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

7 April 2017

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

7 April 2017

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Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

22 April 2017

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MOLREP: an Automated Program for Molecular Replacement

22 April 2017

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Anatomy of CD1-lipid antigen complexes

22 April 2017

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Toward an understanding of NKT cell biology: progress and paradoxes

28 September 2017

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Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides

28 September 2017

1 reference

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Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

28 September 2017

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Lysosomal glycosphingolipid recognition by NKT cells

28 September 2017

1 reference

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Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

28 September 2017

1 reference

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A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan

28 September 2017

1 reference

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CD1d-restricted T cell activation by nonlipidic small molecules

28 September 2017

1 reference

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The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition

28 September 2017

1 reference

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Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells

28 September 2017

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Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

28 September 2017

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Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides

28 September 2017

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Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

28 September 2017

1 reference

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NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells

28 September 2017

1 reference

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Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein

28 September 2017

1 reference

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Cross-presentation of disialoganglioside GD3 to natural killer T cells

28 September 2017

1 reference

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The Paradox of Immune Molecular Recognition of α-Galactosylceramide: Low Affinity, Low Specificity for CD1d, High Affinity for αβ TCRs

28 September 2017

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Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency

28 September 2017

1 reference

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Homo crystallographicus--quo vadis?

28 September 2017

1 reference

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Structural requirements for antigen presentation by mouse CD1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

The molecular basis of CD1-mediated presentation of lipid antigens

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

Structural basis of T cell recognition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045075

Recognition of bacterial glycosphingolipids by natural killer T cells

30 May 2018

1 reference

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

21 January 2018

1 reference

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

21 January 2018

1 reference

Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells

21 January 2018

1 reference

The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex.

21 January 2018

1 reference

Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids

21 January 2018

1 reference

The crystal structure of human CD1d with and without alpha-galactosylceramide

21 January 2018

1 reference

Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCR alpha beta repertoires and differential distribution in lymphoid tissues.

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to Vα14 NKT cells

21 January 2018

1 reference

12 December 2020

CD1-dependent dendritic cell instruction

1 reference

12 December 2020

Distinct Roles of Dendritic Cells and B Cells in Va14Ja18 Natural T Cell Activation In Vivo

1 reference

12 December 2020

Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells

1 reference

12 December 2020

Structure of human CD1b with bound ligands at 2.3 Å, a maze for alkyl chains

1 reference

7 January 2021