Synthetic biology: new engineering rules for an emerging discipline (Q24672399)

Molecular Systems Biology

Europe PubMed Central

title

Synthetic biology: new engineering rules for an emerging discipline (English)

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David K Karig

3

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author name string

Ernesto Andrianantoandro

series ordinal

1

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Subhayu Basu

series ordinal

2

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Ron Weiss

series ordinal

4

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language of work or name

English

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publication date

2006

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published in

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volume

2

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page(s)

2006.0028

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cites work

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Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides

7 April 2017

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7 April 2017

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Intrinsic noise in gene regulatory networks

7 April 2017

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Quorum Sensing in Bacteria

7 April 2017

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Stochastic gene expression in a single cell

7 April 2017

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Environmentally controlled invasion of cancer cells by engineered bacteria

7 April 2017

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Accurate multiplex gene synthesis from programmable DNA microchips

7 April 2017

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Modeling a synthetic multicellular clock: repressilators coupled by quorum sensing

7 April 2017

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Engineered riboregulators enable post-transcriptional control of gene expression

7 April 2017

1 reference

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Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

7 April 2017

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Construction of a genetic toggle switch in Escherichia coli

7 April 2017

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Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

7 April 2017

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Network motifs: simple building blocks of complex networks

7 April 2017

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Network motifs in the transcriptional regulation network of Escherichia coli

7 April 2017

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A synthetic oscillatory network of transcriptional regulators

7 April 2017

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Gene regulation at the single-cell level

7 April 2017

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Noise in eukaryotic gene expression

7 April 2017

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Engineering stability in gene networks by autoregulation

7 April 2017

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Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements

7 April 2017

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Synthetic protein-protein interaction domains created by shuffling Cys2His2 zinc-fingers

7 April 2017

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Foundations for engineering biology

28 September 2017

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Directed evolution of protein switches and their application to the creation of ligand-binding proteins.

28 September 2017

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Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity

28 September 2017

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Ultrasensitivity and noise propagation in a synthetic transcriptional cascade.

28 September 2017

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Directed evolution of Vibrio fischeri LuxR for increased sensitivity to a broad spectrum of acyl-homoserine lactones

28 September 2017

1 reference

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Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Optimizing genetic circuits by global sensitivity analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Periplasmic binding proteins: a versatile superfamily for protein engineering

28 September 2017

1 reference

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Programmable cells: interfacing natural and engineered gene networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Spatiotemporal control of gene expression with pulse-generating networks.

28 September 2017

1 reference

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Superfamilies of evolved and designed networks.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Design of artificial cell-cell communication using gene and metabolic networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Creation of an allosteric enzyme by domain insertion.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

The Coherent Feedforward Loop Serves as a Sign-sensitive Delay Element in Transcription Networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

The engineering of gene regulatory networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Reprogramming control of an allosteric signaling switch through modular recombination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Teleonomic mechanisms in cellular metabolism, growth, and differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Computational design of receptor and sensor proteins with novel functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Directed evolution of a genetic circuit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Assigning numbers to the arrows: parameterizing a gene regulation network by using accurate expression kinetics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Synchronizing genetic relaxation oscillators by intercell signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Dissecting the functional program of Escherichia coli promoters: the combined mode of action of Lac repressor and AraC activator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Improving lycopene production in Escherichia coli by engineering metabolic control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Simulation of prokaryotic genetic circuits

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Artificial cell-cell communication in yeast Saccharomyces cerevisiae using signaling elements from Arabidopsis thaliana

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Synthetic biology. Synthetic biology remakes small genomes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Long-term monitoring of bacteria undergoing programmed population control in a microchemostat

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

A synthetic gene-metabolic oscillator.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

A synthetic multicellular system for programmed pattern formation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Programmable ligand-controlled riboregulators of eukaryotic gene expression.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Signal-amplifying genetic circuit enables in vivo observation of weak promoter activation in the Rhl quorum sensing system.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

BioLogic gates enable logical transcription control in mammalian cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Computational design of a biologically active enzyme

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Programmed population control by cell-cell communication and regulated killing.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Biological networks: the tinkerer as an engineer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Response delays and the structure of transcription networks.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

Genomics. Tinker, tailor: can Venter stitch together a genome from scratch?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1681505

DNA ligation by selection

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16738572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene regulation by proteins acting nearby and at a distance

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMSB4100073

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MSB4100073

1 reference

238511

238511

1 reference

1 reference

1 reference