Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes (Q24673517)

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English	Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes	scientific article

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11 November 2019

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes (English)

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11 November 2019

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glyceryl 2-arachidonate

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Juha Savinainen

1

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11 November 2019

Jarmo T Laitinen

4

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11 November 2019

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T Järvinen

2

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11 November 2019

K Laine

3

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11 November 2019

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1 October 2001

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11 November 2019

British Journal of Pharmacology

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11 November 2019

134

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11 November 2019

3

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11 November 2019

664-672

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11 November 2019

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

7 April 2017

CB1 receptor-G protein association. Subtype selectivity is determined by distinct intracellular domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

7 April 2017

Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

7 April 2017

Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

7 April 2017

A second endogenous cannabinoid that modulates long-term potentiation

1 reference

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7 April 2017

Molecular characterization of a peripheral receptor for cannabinoids

1 reference

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7 April 2017

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1 reference

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7 April 2017

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

1 reference

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7 April 2017

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1 reference

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7 April 2017

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

1 reference

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7 April 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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7 April 2017

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

1 reference

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7 April 2017

Neuropharmacology and therapeutic potential of cannabinoids

1 reference

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28 September 2017

Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

28 September 2017

Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

1 reference

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28 September 2017

Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

28 September 2017

Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

28 September 2017

mu-Opioid receptor-stimulated guanosine-5'-O-(gamma-thio)-triphosphate binding in rat thalamus and cultured cell lines: signal transduction mechanisms underlying agonist efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

28 September 2017

Agonist selective regulation of G proteins by cannabinoid CB(1) and CB(2) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

30 May 2018

Influence of G protein type on agonist efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

30 May 2018

Activation of various subtypes of G-protein alpha subunits by partial agonists of the adenosine A1 receptor

1 reference

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30 May 2018

Interaction of 5-HT1B/D ligands with recombinant h 5-HT1A receptors: intrinsic activity and modulation by G-protein activation state

1 reference

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30 May 2018

[Gamma-35S]GTP autoradiography allows region-specific detection of muscarinic receptor-dependent G-protein activation in the chick optic tectum

1 reference

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30 May 2018

Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

30 May 2018

Effects of chronic treatment with delta9-tetrahydrocannabinol on cannabinoid-stimulated [35S]GTPgammaS autoradiography in rat brain

1 reference

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30 May 2018

Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide.

1 reference

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28 November 2018

The CB(1) cannabinoid receptor juxtamembrane C-terminal peptide confers activation to specific G proteins in brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

28 November 2018

Selective detection of adenosine A1 receptor-dependent G-protein activity in basal and stimulated conditions of rat brain [35S]guanosine 5'-(gamma-thio)triphosphate autoradiography

1 reference

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28 November 2018

Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors

1 reference

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28 November 2018

Cannabinoid receptor agonist efficacy for stimulating [35S]GTPgammaS binding to rat cerebellar membranes correlates with agonist-induced decreases in GDP affinity.

1 reference

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28 November 2018

Interaction of full and partial agonists of the A1 adenosine receptor with receptor/G protein complexes in rat brain membranes.

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28 November 2018

Measurement of guanine nucleotide-binding protein activation by A1 adenosine receptor agonists in bovine brain membranes: stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572991

28 November 2018

Cannabinoid agonist signal transduction in rat brain: comparison of cannabinoid agonists in receptor binding, G-protein activation, and adenylyl cyclase inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoid receptor stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding in rat brain membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cannabinoid receptors in rat brain by WIN 55212-2 produces coupling to multiple G protein alpha-subunits with different potencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/SJ.BJP.0704297

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11 November 2019

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Consolidated OpenCitations Corpus – April 2017

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2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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11 November 2019

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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11 November 2019

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