The astacin family of metalloendopeptidases (Q24675114)

Evolutionary families of peptidases

Europe PubMed Central

title

The astacin family of metalloendopeptidases (English)

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author name string

J S Bond

series ordinal

1

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R J Beynon

series ordinal

2

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language of work or name

English

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publication date

July 1995

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published in

Protein Science

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volume

4

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issue

7

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page(s)

1247-61

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cites work

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7 April 2017

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An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin

7 April 2017

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Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains

7 April 2017

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Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues

7 April 2017

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The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases

7 April 2017

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Novel regulators of bone formation: molecular clones and activities

7 April 2017

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Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity

7 April 2017

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Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases

7 April 2017

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

7 April 2017

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Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

7 April 2017

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Mapping of the bone morphogenetic protein 1 gene (BMP1) to 8p21: removal of BMP1 from candidacy for the bone disorder in Langer-Giedion syndrome

7 April 2017

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The structural genes, MEP1A and MEP1B, for the alpha and beta subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively

7 April 2017

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Purification of meprin from human kidney and its role in parathyroid hormone degradation

7 April 2017

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The molecular basis of blood coagulation

7 April 2017

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Cloning, expression, and chromosomal localization of the mouse meprin beta subunit

7 April 2017

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Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

7 April 2017

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The CUB domain. A widespread module in developmentally regulated proteins

7 April 2017

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Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo

28 September 2017

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An adhesive domain detected in functionally diverse receptors

28 September 2017

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A new member to the astacin family of metalloendopeptidases: a novel 1,25-dihydroxyvitamin D-3-stimulated mRNA from chorioallantoic membrane of quail.

28 September 2017

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Complement factor I and cofactors in control of complement system convertase enzymes

28 September 2017

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Cloning and expression of cDNA encoding Xenopus laevis bone morphogenetic protein-1 during early embryonic development

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Characterization of a homolog of human bone morphogenetic protein 1 in the embryo of the sea urchin, Strongylocentrotus purpuratus.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

HCE, a constituent of the hatching enzymes of Oryzias latipes embryos, releases unique proline-rich polypeptides from its natural substrate, the hardened chorion

28 September 2017

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COOH-terminal proteolytic processing of secreted and membrane forms of the alpha subunit of the metalloprotease meprin A. Requirement of the I domain for processing in the endoplasmic reticulum

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Molecular cloning and sequence analysis of flavastacin: an O-glycosylated prokaryotic zinc metalloendopeptidase

28 September 2017

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28 September 2017

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Expression of meprin subunit precursors. Membrane anchoring through the beta subunit and mechanism of zymogen activation

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Meprin: a membrane-bound metallo-endopeptidase.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

A unique proteolytic action of HCE, a constituent protease of a fish hatching enzyme: tight binding to its natural substrate, egg envelope

28 September 2017

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Isolation and some properties of low choriolytic enzyme (LCE), a component of the hatching enzyme of the teleost, Oryzias latipes

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Purification and partial characterization of high choriolytic enzyme (HCE), a component of the hatching enzyme of the teleost, Oryzias latipes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Two constituent proteases of a teleostean hatching enzyme: concurrent syntheses and packaging in the same secretory granules in discrete arrangement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Molecular approach to dorsoanterior development in Xenopus laevis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

The matrix-degrading metalloproteinases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Families of metalloendopeptidases and their relationships

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Spatial and temporal expression pattern during sea urchin embryogenesis of a gene coding for a protease homologous to the human protein BMP-1 and to the product of the Drosophila dorsal-ventral patterning gene tolloid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Expression of rat endopeptidase-24.18 in COS-1 cells: membrane topology and activity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Characterization of meprin, a membrane-bound metalloendopeptidase from mouse kidney

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Proteins of the kidney microvillar membrane. Structural and immunochemical properties of rat endopeptidase-2 and its immunohistochemical localization in tissues of rat and mouse

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Homo- and heterotetrameric forms of the membrane-bound metalloendopeptidases meprin A and B.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Mapping the active site of meprin-A with peptide substrates and inhibitors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Hydrolysis of transforming growth factor-alpha by cell-surface peptidases in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Cloning a rat meprin cDNA reveals the enzyme is a heterodimer

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Immunohistochemical localization of the metalloproteinase meprin in salivary glands of male and female mice

19 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

The metabolism of neuropeptides. Hydrolysis of peptides by the phosphoramidon-insensitive rat kidney enzyme 'endopeptidase-2' and by rat microvillar membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

Implications of the three-dimensional structure of astacin for the structure and function of the astacin family of zinc-endopeptidases.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Biosynthesis and degradation of meprins, kidney brush border proteinases

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Characterization of tolloid-related-1: a BMP-1-like product that is required during larval and pupal stages of Drosophila development

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Tissue-specific expression and chromosomal localization of the alpha subunit of mouse meprin A.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase: a metalloendopeptidase of the human intestinal microvillus membrane which degrades biologically active peptides.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143163

Distribution of, and a putative role for, the cell-surface neutral metallo-endopeptidases during mammalian craniofacial development

28 November 2018

1 reference

12 December 2020

A membrane-bound metallo-endopeptidase from rat kidney: its immunological characterization

1 reference

12 December 2020

An interspecific backcross linkage map of the proximal half of mouse chromosome 14

1 reference

12 December 2020

A membrane-bound metallo-endopeptidase from rat kidney hydrolyzing parathyroid hormone. Purification and characterization

1 reference

12 December 2020

Spatial expression of the hatching enzyme gene in the sea urchin embryo

1 reference

12 December 2020

Membrane association and oligomeric organization of the alpha and beta subunits of mouse meprin A

1 reference

12 December 2020

The univin gene encodes a member of the transforming growth factor-beta superfamily with restricted expression in the sea urchin embryo

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Biosynthesis of Astacus protease, a digestive enzyme from crayfish

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

The role of vitamin D in chorioallantoic membrane calcium transport

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Rat endopeptidase-24.18 alpha subunit is secreted into the culture medium as a zymogen when expressed by COS-1 cells

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1.

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Epidermal growth factor-like modules

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Amino acid sequence of a unique protease from the crayfish Astacus fluviatilis.

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Role of transmembrane domain interactions in the assembly of class II MHC molecules

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Distribution of meprin in kidneys from mice with high- and low-meprin activity

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

The plasminogen activator/plasmin system

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560040701

7 January 2021

Identifiers

DOI

10.1002/PRO.5560040701

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4613263

4613263

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1 reference

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