Genetic targeting of the kinase activity of the Met receptor in cancer cells (Q24675200)

5

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Sabrina Arena

object named as

Sabrina Arena

1

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Massimiliano Mazzone

object named as

Massimiliano Mazzone

3

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Paolo M. Comoglio

object named as

Paolo Maria Comoglio

4

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author name string

Alberto Pisacane

Proceedings of the National Academy of Sciences of the United States of America

2

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language of work or name

English

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publication date

3 July 2007

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published in

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volume

104

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issue

27

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page(s)

11412-7

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cites work

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A census of human cancer genes

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Invasive growth: a MET-driven genetic programme for cancer and stem cells

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Targeting the c-Met signaling pathway in cancer

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The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants

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Met, metastasis, motility and more

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A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

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The semaphorin 4D receptor controls invasive growth by coupling with Met

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Comparing antibody and small-molecule therapies for cancer

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Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis

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Somatic mutations lead to an oncogenic deletion of met in lung cancer

28 September 2017

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Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.

28 September 2017

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Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family

28 September 2017

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A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.

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Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis.

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An uncleavable form of pro–scatter factor suppresses tumor growth and dissemination in mice

21 January 2018

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Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

21 January 2018

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https://pubmed.ncbi.nlm.nih.gov/17595299

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of Met protein in thyroid tumours

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