The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission (Q24676135)

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7 January 2021

Nicotinic acetylcholine receptor at 9 A resolution.

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7 January 2021

Projection structure of the nicotinic acetylcholine receptor: distinct conformations of the alpha subunits.

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7 January 2021

Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The nicotinic acetylcholine receptor of the Torpedo electric ray.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Effects of mutating leucine to threonine in the M2 segment of alpha1 and beta1 subunits of GABAA alpha1beta1 receptors

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7 January 2021

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Reconstruction of three-dimensional images from electron micrographs of structures with helical symmetry

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Molecular structure determination by electron microscopy of unstained crystalline specimens

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Analysis of transient structures by cryo-microscopy combined with rapid mixing of spray droplets

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7 January 2021

The structure of ion channels in membranes of excitable cells

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7 January 2021

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Structure of nicotinic acetylcholine receptors

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

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7 January 2021

Single channel currents in the nicotinic acetylcholine receptor: a direct demonstration of allosteric transitions

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7 January 2021

Electrostatics and the ion selectivity of ligand-gated channels

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7 January 2021

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Electron microscopy of frozen hydrated biological specimens

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Distortion correction of tubular crystals: improvements in the acetylcholine receptor structure

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The location of the gate in the acetylcholine receptor channel.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Allosteric receptors after 30 years

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Cryo-electron microscopy of vitrified specimens

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

How fast does an acetylcholine receptor channel open? Laser-pulse photolysis of an inactive precursor of carbamoylcholine in the microsecond time region with BC3H1 cells

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Mapping of the acetylcholine binding site of the nicotinic acetylcholine receptor: [3H]nicotine as an agonist photoaffinity label

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Molecular forms of acetylcholine receptor. Effects of calcium ions and a sulfhydryl reagent on the occurrence of oligomers

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Reconstruction of three dimensional structures from electron micrographs

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Energy of an Ion crossing a Low Dielectric Membrane: Solutions to Four Relevant Electrostatic Problems

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7 January 2021

Permeability of cell junction depends on local cytoplasmic calcium activity

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7 January 2021

Three-dimensional model of purple membrane obtained by electron microscopy

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7 January 2021

Structure of the junction between communicating cells

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7 January 2021

Two configurations of a channel-forming membrane protein

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7 January 2021

Quaternary structure of the acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Ion channel of acetylcholine receptor reconstructed from images of postsynaptic membranes

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Molecular mechanism of vectorial proton translocation by bacteriorhodopsin

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Transport, capture and exocytosis of single synaptic vesicles at active zones

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7 January 2021

Acetylcholine receptor channel imaged in the open state

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Functional characterization of a potassium-selective prokaryotic glutamate receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Seeing is relieving: electrical synapses between visualized neurons

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Cloning of a new gap junction gene (Cx36) highly expressed in mammalian brain neurons.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Dynamics and orientation of N+(CD3)3-bromoacetylcholine bound to its binding site on the nicotinic acetylcholine receptor.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

CRYSTAL STRUCTURE AND INFORMATION THEORY.

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7 January 2021

Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Crystalline arrays of membrane-bound acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Structure of the nicotinic receptor acetylcholine-binding site. Identification of acidic residues in the delta subunit within 0.9 nm of the 5 alpha subunit-binding

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Identification of amino acids contributing to high and low affinity d-tubocurarine sites in the Torpedo nicotinic acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Probing the structure of the nicotinic acetylcholine receptor ion channel with the uncharged photoactivable compound -3H-diazofluorene

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Location of subunits within the acetylcholine receptor by electron image analysis of tubular crystals from Torpedo marmorata

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Three-dimensional structure of the acetylcholine receptor by cryoelectron microscopy and helical image reconstruction

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Organization of acetylcholine receptors in quick-frozen, deep-etched, and rotary-replicated Torpedo postsynaptic membrane

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Calcium-mediated changes in gap junction structure: evidence from the low angle X-ray pattern

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Ultrastructural localization of the Mr 43,000 protein and the acetylcholine receptor in Torpedo postsynaptic membranes using monoclonal antibodies

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Tubular crystals of acetylcholine receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The extracellular linker of muscle acetylcholine receptor channels is a gating control element

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Electron microscopy of frozen biological suspensions

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Primary structure of delta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The crystal structure of a five-stranded coiled coil in COMP: a prototype ion channel?

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Three-dimensional structure of a recombinant gap junction membrane channel

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The cavity and pore helices in the KcsA K+ channel: electrostatic stabilization of monovalent cations.

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Structural rearrangements underlying K+-channel activation gating

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

The structural era of endocytosis

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Redesigning trypsin: alteration of substrate specificity

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Gap junctional conductance is a simple and sensitive function of intracellular pH

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021

Nicotinic receptor of acetylcholine: structure of an oligomeric integral membrane protein

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https://api.crossref.org/works/10.1098%2FRSTB.2000.0737

7 January 2021