Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1 (Q24676147)

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English	Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1	scientific article

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scholarly article

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Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1 (English)

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author name string

Emily L Abbot

1

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Danielle S Grenade

2

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David J Kennedy

3

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Kelly M Gatfield

4

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David T Thwaites

5

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language of work or name

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publication date

February 2006

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British Journal of Pharmacology

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147

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3

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298-306

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Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751303

7 April 2017

Identification and characterization of a lysosomal transporter for small neutral amino acids

1 reference

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LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine

1 reference

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The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons

1 reference

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Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters

1 reference

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Ocular complications of neurological therapy

1 reference

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Indirect regulation of the intestinal H+-coupled amino acid transporter hPAT1 (SLC36A1).

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H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.

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Substrate recognition by the mammalian proton-dependent amino acid transporter PAT1.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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H(+)/solute-induced intracellular acidification leads to selective activation of apical Na(+)/H(+) exchange in human intestinal epithelial cells

1 reference

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New antiepileptic drugs

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1 reference

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Nuclear magnetic resonance detection of increased cortical GABA in vigabatrin-treated rats in vivo.

1 reference

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D-cycloserine uses an active transport mechanism in the human intestinal cell line Caco 2.

1 reference

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.gamma.-Aminobutyric acid agonists, antagonists, and uptake inhibitors. Design and therapeutic aspects

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Human brain gamma-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy.

1 reference

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D-cycloserine transport in human intestinal epithelial (Caco-2) cells: mediation by a H(+)-coupled amino acid transporter

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1.

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1 reference

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1 reference

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1 reference

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28 November 2018

Specificity of the imino acid carrier in rat small intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751303

28 November 2018

H+-zwitterionic amino acid symport at the brush-border membrane of human intestinal epithelial (CACO-2) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16331283

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Amino acid transport by the small intestine of the rat. The existence and specificity of the transport mechanism of imino acids and its relation to the transport of glycine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16331283

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16331283

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inferred from PubMed ID database lookup

A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16331283

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Determination of GABA and vigabatrin in human plasma by a rapid and simple HPLC method: correlation between clinical response to vigabatrin and increase in plasma GABA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16331283

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New Antiepileptic Drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0706557

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Identifiers

10.1038/SJ.BJP.0706557

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