Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene (Q24676918)

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I M Mansuy

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S G Grant

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M Mayford

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E R Kandel

Proceedings of the National Academy of Sciences of the United States of America

6

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language of work or name

English

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publication date

29 April 1997

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published in

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volume

94

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issue

9

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page(s)

4761-5

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cites work

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Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

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Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system

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Control of memory formation through regulated expression of a CaMKII transgene

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Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo

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Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation

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Ca(2+)-independent reduction of N-methyl-D-aspartate channel activity by protein tyrosine phosphatase

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NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice

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The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line

28 September 2017

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The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B

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Initial events of myelination involve Fyn tyrosine kinase signalling

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A generic intron increases gene expression in transgenic mice

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CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx

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Modulation of GABAA receptors by tyrosine phosphorylation

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In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brain

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Detection of mRNAs Encoding Distinct Isoenzymes of Type II Calcium/Calmodulin‐Dependent Protein Kinase Using the Polymerase Chain Reaction

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Increased fearfulness of Fyn tyrosine kinase deficient mice.

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Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

21 January 2018

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Tyrosine kinase phosphorylation of GABAA receptors

21 January 2018

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PSA-NCAM is required for activity-induced synaptic plasticity.

21 January 2018

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Protein tyrosine kinase-mediated potentiation of currents from cloned NMDA receptors.

21 January 2018

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Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

28 November 2018

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Modified hippocampal long-term potentiation in PKCγ-mutant mice

21 January 2018

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Expression of a novel form of the fyn proto-oncogene in hematopoietic cells

21 January 2018

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12 December 2020

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

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12 December 2020

Regional localization of Fyn in adult brain; studies with mice in which fyn gene was replaced by lacZ

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12 December 2020

Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

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12 December 2020

Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice

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12 December 2020

NMDA receptor subunits epsilon 1 (NR2A) and epsilon 2 (NR2B) are substrates for Fyn in the postsynaptic density fraction isolated from the rat brain

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12 December 2020

Fyn tyrosine kinase is required for normal amygdala kindling

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12 December 2020

Identifiers

DOI

10.1073/PNAS.94.9.4761

1 reference

ADS bibcode

1997PNAS...94.4761K

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1 reference

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PubMed publication ID

9114065

1 reference