Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis (Q24679698)

1

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Weijie Li

2

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Yoshiyuki Yasuda

3

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Wolfgang Wienhold

4

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Lisa K Denzin

5

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Alfred Lautwein

6

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Christoph Driessen

7

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Petra Schnorrer

8

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Ekkehard Weber

9

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Raffael Kurek

11

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Arthur Melms

12

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Dieter Bromme

Journal of Clinical Investigation

13

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language of work or name

English

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publication date

August 2003

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published in

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volume

112

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issue

4

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page(s)

517-26

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cites work

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Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

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HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading

7 April 2017

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L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

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Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization

7 April 2017

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Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

7 April 2017

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Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs

7 April 2017

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28 September 2017

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CLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing

28 September 2017

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Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravis

28 September 2017

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Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

28 September 2017

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Proteolysis in MHC class II antigen presentation: who's in charge?

28 September 2017

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Cathepsins and compartmentalization in antigen presentation

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28 September 2017

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An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

28 September 2017

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Cathepsin S activity regulates antigen presentation and immunity

28 September 2017

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28 September 2017

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Selectivity of the major histocompatibility complex class II presentation pathway of cortical thymic epithelial cell lines

28 September 2017

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Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

28 September 2017

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Assembly, transport, and function of MHC class II molecules

28 September 2017

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Monensin prevents terminal glycosylation of the N- and O-linked oligosaccharides of the HLA-DR-associated invariant chain and inhibits its dissociation from the alpha-beta chain complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Microenvironments in the normal thymus and the thymus in myasthenia gravis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Intrathymic pathogenesis and dual genetic control of myasthenia gravis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Trafficking of major histocompatibility complex class II molecules through intracellular compartments containing HLA-DM.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Quantification of cathepsins B and L in cells

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

High level expression and crystallization of recombinant human cathepsin S

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Individual cathepsins degrade immune complexes internalized by antigen-presenting cells via Fcgamma receptors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

The antigen presentation pathway in medullary thymic epithelial cells, but not that in cortical thymic epithelial cells, conforms to the endocytic pathway.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171390

Paraneoplastic myasthenia gravis correlates with generation of mature naive CD4+ T cells in thymomas

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925692

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Using thymus anatomy to dissect T cell repertoire selection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925692

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925692