Smad4 is critical for self-renewal of hematopoietic stem cells (Q24679788)

2

object named as

Ulrika Blank

0 references

author name string

Jennifer L Moody

3

0 references

Mats Ehinger

4

0 references

Sofie Singbrant

5

0 references

Chu-Xia Deng

6

0 references

Stefan Karlsson

Journal of Experimental Medicine

7

0 references

language of work or name

English

0 references

publication date

19 March 2007

0 references

published in

0 references

volume

204

0 references

issue

3

0 references

page(s)

467-74

0 references

cites work

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

A role for Wnt signalling in self-renewal of haematopoietic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Osteoblastic cells regulate the haematopoietic stem cell niche

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Inducible gene targeting in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

A road map toward defining the role of Smad signaling in hematopoietic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Autocrine transforming growth factor-beta regulation of hematopoiesis: many outcomes that depend on the context

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

The role of Smad signaling in hematopoiesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137898

Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable

30 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060465

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060465

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060465

Smad4 signalling in T cells is required for suppression of gastrointestinal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060465

Smad7 promotes self-renewal of hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060465

Roles for c-Myc in self-renewal of hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060465

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17353364

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Generation of Smad4/Dpc4 conditional knockout mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17353364