Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior (Q24679793)

1

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Deqiang Jing

2

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Kevin G Bath

3

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Alessandro Ieraci

4

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Tanvir Khan

5

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Chia-Jen Siao

6

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Daniel G Herrera

7

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Miklos Toth

8

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Chingwen Yang

9

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Barbara L Hempstead

11

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Francis S Lee

Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.

12

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language of work or name

English

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publication date

6 October 2006

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published in

Science

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volume

314

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page(s)

140-3

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issue

5796

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cites work

1 reference

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Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

7 April 2017

1 reference

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Essential role of brain-derived neurotrophic factor in adult hippocampal function

7 April 2017

1 reference

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

7 April 2017

1 reference

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The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Association of a functional BDNF polymorphism and anxiety-related personality traits

7 April 2017

1 reference

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Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test

28 September 2017

1 reference

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Pro-region of neurotrophins: role in synaptic modulation

28 September 2017

1 reference

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Plasticity of the hippocampus: adaptation to chronic stress and allostatic load.

28 September 2017

1 reference

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Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

A molecular and cellular theory of depression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

The brain-derived neurotrophic factor Val66Met polymorphism is associated with sense of coherence in a non-clinical community sample of 7335 adults.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Examination of behavioral deficits triggered by targeting Bdnf in fetal or postnatal brains of mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Brain-derived neurotrophic factor plays a critical role in contextual fear conditioning.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Effects of chronic fluoxetine in animal models of anxiety and depression.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Ethnic difference of the BDNF 196G/A (val66met) polymorphism frequencies: the possibility to explain ethnic mental traits.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1880880

Determination of fractal dimension of physiologically characterized neurons in two and three dimensions

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17023662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1129663

1 reference

810733

810733

1 reference

1 reference

1 reference