Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract (Q24680138)

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Language	Label	Description	Also known as
English	Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract	scientific article

Statements

scholarly article

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Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract (English)

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based on heuristic

inferred from title

prostate cancer

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based on heuristic

inferred from title

Phellodendron amurense

object named as

Phellodendron amurense

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based on heuristic

inferred from title

author name string

Addanki P Kumar

1

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Shylesh Bhaskaran

2

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Manonmani Ganapathy

3

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Katherine Crosby

4

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Michael D Davis

5

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Peter Kochunov

6

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John Schoolfield

7

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I-Tien Yeh

8

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Dean A Troyer

9

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Rita Ghosh

10

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language of work or name

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publication date

1 May 2007

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Clinical Cancer Research

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13

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9

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2784-94

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Akt-and CREB-mediated prostate cancer cell proliferation inhibition by Nexrutine, a Phellodendron amurense extract

1 reference

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EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

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Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence

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7 April 2017

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

7 April 2017

CREB is a regulatory target for the protein kinase Akt/PKB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

7 April 2017

Cancer statistics, 2006

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7 April 2017

Cancer chemoprevention with dietary phytochemicals

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7 April 2017

Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer

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Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward

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2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6.

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28 September 2017

Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis

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28 September 2017

A prospective study of lycopene and tomato product intake and risk of prostate cancer

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28 September 2017

Role of diet in prostate cancer development and progression

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28 September 2017

CREB: the unindicted cancer co-conspirator

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28 September 2017

Tomatoes or lycopene: a role in prostate carcinogenesis?

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28 September 2017

Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0 ng/ml or lower

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The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia

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Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway

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Targeting multiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy

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28 September 2017

Pomegranate extracts potently suppress proliferation, xenograft growth, and invasion of human prostate cancer cells

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28 September 2017

Detection of prostate cancer and predicting progression: current and future diagnostic markers

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28 September 2017

Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.

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28 September 2017

The role of cyclic-AMP binding protein (CREB) in leukemia cell proliferation and acute leukemias

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28 September 2017

4-Hydroxy-3-methoxybenzoic acid methyl ester: a curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: potential for prostate cancer management

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 September 2017

Role of the PKA-regulated transcription factor CREB in development and tumorigenesis of endocrine tissues.

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28 September 2017

Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer

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28 September 2017

Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 September 2017

Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders.

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28 September 2017

Research into complementary and alternative medicine: problems and potential

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28 September 2017

Molecular genetics of prostate cancer.

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28 September 2017

Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element

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28 September 2017

Aberrant expression of cAMP-response-element-binding protein ('CREB') induces apoptosis.

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28 September 2017

Nutrition and prostate cancer

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28 September 2017

Metastatic prostate cancer in a transgenic mouse

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28 September 2017

Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses

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28 September 2017

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 September 2017

Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model

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30 May 2018

Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells.

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30 May 2018

Phosphorylation of the EWS IQ domain regulates transcriptional activity of the EWS/ATF1 and EWS/FLI1 fusion proteins

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30 May 2018

E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse

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30 May 2018

Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 November 2018

Interference with 3',5'-cyclic adenosine monophosphate response element binding protein stimulates apoptosis through aberrant cell cycle progression and checkpoint activation.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 November 2018

Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 November 2018

Platelet-activating factor mediates MMP-2 expression and activation via phosphorylation of cAMP-response element-binding protein and contributes to melanoma metastasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 November 2018

Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948816

28 November 2018

A prospective clinical trial of green tea for hormone refractory prostate cancer: an evaluation of the complementary/alternative therapy approach

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28 November 2018

Dietary genistein improves survival and reduces expression of osteopontin in the prostate of transgenic mice with prostatic adenocarcinoma (TRAMP).

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28 November 2018

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28 November 2018

Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP).

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28 November 2018

2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells

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28 November 2018

Malignant changes in the prostate with ageing

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https://pubmed.ncbi.nlm.nih.gov/17473212

12 December 2020

based on heuristic

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Pathologic progression of autochthonous prostate cancer in the TRAMP model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17473212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17473212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB and its associated proteins act as survival factors for human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17473212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/17473212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17473212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-06-2974

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