Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction (Q24683196)

2

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H Vorum

3

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H Hager

4

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C M Petersen

5

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H Røigaard

6

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H Y Min

7

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F Vilhardt

8

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L B Møller

9

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S Kornfeld

10

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J Gliemann

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

11

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language of work or name

English

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publication date

4 May 1998

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published in

Journal of Cell Biology

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volume

141

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issue

3

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page(s)

815-28

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cites work

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The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

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Localization of the insulin-like growth factor II binding site to amino acids 1508-1566 in repeat 11 of the mannose 6-phosphate/insulin-like growth factor II receptor

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Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liver

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Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin

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Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

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alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor

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Herpes simplex virus glycoprotein D acquires mannose 6-phosphate residues and binds to mannose 6-phosphate receptors.

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Localization of transferrin receptors and insulin-like growth factor II receptors in vesicles from 3T3-L1 adipocytes that contain intracellular glucose transporters

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Lysosomal degradation of receptor-bound urokinase-type plasminogen activator is enhanced by its inhibitors in human trophoblastic choriocarcinoma cells

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Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes

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28 September 2017

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28 September 2017

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The urokinase-type plasminogen activator system in cancer metastasis: a review

28 September 2017

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The bovine mannose 6-phosphate/insulin-like growth factor II receptor. The role of arginine residues in mannose 6-phosphate binding.

30 May 2018

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Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes

30 May 2018

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Laurate binding to human serum albumin. Multiple binding equilibria investigated by a dialysis exchange method.

30 May 2018

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Purification, biochemical composition, and biosynthesis of the Mo3 activation antigen expressed on the plasma membrane of human mononuclear phagocytes.

30 May 2018

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Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cells

30 May 2018

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Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain

30 May 2018

1 reference

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Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator

30 May 2018

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Structural requirements for glycosyl-phosphatidylinositol-anchor attachment in the cellular receptor for urokinase plasminogen activator

30 May 2018

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Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptor

30 May 2018

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The Two Mannose 6-Phosphate Receptors Transport Distinct Complements of Lysosomal Proteins

30 May 2018

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Crossref

https://api.crossref.org/works/10.1083%2FJCB.141.3.815

Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132758

Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta 1 precursor.

28 November 2018

1 reference

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Ligand binding specificities of the two mannose 6-phosphate receptors

28 November 2018

1 reference

12 December 2020

A soluble, ligand binding mutant of the human urokinase plasminogen activator receptor

1 reference

12 December 2020

Analysis of ligand recognition by the purified alpha 2-macroglobulin receptor (low density lipoprotein receptor-related protein). Evidence that high affinity of alpha 2-macroglobulin-proteinase complex is achieved by binding to adjacent receptors

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12 December 2020

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes

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12 December 2020

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds lipoprotein lipase and beta-migrating very low density lipoprotein associated with the lipase

1 reference

12 December 2020

TGF-beta: structure, function, and formation

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12 December 2020

Urokinase receptor. An activation antigen in human T lymphocytes

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12 December 2020

Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta

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12 December 2020

A cleaved form of the receptor for urokinase-type plasminogen activator in invasive transplanted human and murine tumors

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12 December 2020

Identification of the urokinase receptor as an adhesion receptor for vitronectin

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12 December 2020

Functional role of cell surface integrins on human trophoblast cell migration: regulation by TGF-beta, IGF-II, and IGFBP-1

1 reference

12 December 2020

The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility

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12 December 2020

Transforming Growth Factor-Beta Receptors and Mannose 6-Phosphate/Insulin-Like Growth Factor-II Receptor Expression in Human Hepatocellular Carcinoma

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12 December 2020

On the preparation of cryosections for immunocytochemistry

1 reference

12 December 2020

The chicken liver cation-independent mannose 6-phosphate receptor lacks the high affinity binding site for insulin-like growth factor II

1 reference

12 December 2020

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

1 reference

12 December 2020

Chicken and Xenopus mannose 6-phosphate receptors fail to bind insulin-like growth factor II

1 reference

12 December 2020

The urokinase receptor is a major vitronectin-binding protein on endothelial cells

1 reference

12 December 2020

Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.141.3.815

1 reference

1 reference

1 reference

PubMed publication ID

9566979

1 reference