Chromosome breakage after G2 checkpoint release (Q24683383)

2

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Andrea Krempler

3

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Leopoldine Tchouandong

4

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Andrea Beucher

5

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Sarah Walker

6

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Tom Stiff

7

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Penny Jeggo

8

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Markus Löbrich

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

9

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language of work or name

English

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publication date

12 March 2007

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published in

Journal of Cell Biology

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volume

176

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issue

6

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page(s)

749-55

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cites work

1 reference

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Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response

7 April 2017

1 reference

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Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

7 April 2017

1 reference

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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Megabase chromatin domains involved in DNA double-strand breaks in vivo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

7 April 2017

1 reference

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Structural basis for Chk1 inhibition by UCN-01

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

7 April 2017

1 reference

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Histone H2A variants H2AX and H2AZ

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Chromosomal stability and the DNA double-stranded break connection

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Pathways of DNA double-strand break repair during the mammalian cell cycle

7 April 2017

1 reference

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7 April 2017

1 reference

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Early events in the DNA damage response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Low-dose hyper-radiosensitivity: a consequence of ineffective cell cycle arrest of radiation-damaged G2-phase cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Mechanism and regulation of human non-homologous DNA end-joining

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Detection of repair activity during the DNA damage-induced G2 delay in human cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: joining of correct and incorrect ends

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs) of the Chinese hamster ovary cell line.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064048

Methods for the Quantification of DNA Double-Strand Breaks Determined from the Distribution of DNA Fragment Sizes Measured by Pulsed-Field Gel Electrophoresis

30 May 2018

1 reference

12 December 2020

A method for detecting sister chromatid exchanges using prematurely condensed chromosomes and immunogold-silver staining

1 reference

12 December 2020

Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia

1 reference

12 December 2020

On the nature of a defect in cells from individuals with ataxia-telangiectasia

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200612047

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1 reference

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PubMed publication ID

17353355

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