Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis (Q24683896)

Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells

Europe PubMed Central

title

Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis (English)

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Roger Abounader

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John Laterra

series ordinal

2

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language of work or name

English

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publication date

October 2005

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published in

Neuro-Oncology

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volume

7

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issue

4

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page(s)

436-51

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cites work

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Scatter factor/hepatocyte growth factor is essential for liver development

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Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation

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Hepatocyte growth factor/c-Met signaling promotes the progression of experimental human neuroblastomas

28 September 2017

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Vascular gene expression in nonneoplastic and malignant brain.

28 September 2017

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Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation.

28 September 2017

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Functional map and domain structure of MET, the product of the c- met protooncogene and receptor for hepatocyte growth factor/scatter factor

28 September 2017

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Increased Sp1 phosphorylation as a mechanism of hepatocyte growth factor (HGF/SF)-induced vascular endothelial growth factor (VEGF/VPF) transcription

28 September 2017

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Hepatocyte growth factor-induced endothelial cell motility is mediated by the upregulation of inducible nitric oxide synthase expression

28 September 2017

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Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription

28 September 2017

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28 September 2017

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Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo

28 September 2017

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Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells

28 September 2017

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Hepatocyte growth factor enhances MMP activity in human endothelial cells

28 September 2017

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Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas

28 September 2017

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Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells

28 September 2017

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Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells

28 September 2017

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Met and hepatocyte growth factor/scatter factor expression in human gliomas

28 September 2017

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28 September 2017

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Scatter factor/hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth

28 September 2017

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Angiogenesis as a component of epithelial-mesenchymal interactions.

28 September 2017

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Oncogene amplification in human gliomas: a molecular cytogenetic analysis

28 September 2017

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Scatter factor induces blood vessel formation in vivo

28 September 2017

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Organization of the human hepatocyte growth factor-encoding gene

28 September 2017

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Evidence for the identity of human scatter factor and human hepatocyte growth factor

28 September 2017

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Scatter factor expression and regulation in human glial tumors

28 September 2017

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Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor

28 September 2017

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Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas

30 May 2018

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30 May 2018

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Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

An epithelial scatter factor released by embryo fibroblasts.

30 May 2018

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Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

30 May 2018

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Frequent amplification of the c-met gene in scirrhous type stomach cancer.

30 May 2018

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Comparative analysis of expression of hepatocyte growth factor and its receptor, c-met, in gliomas, meningiomas and schwannomas in humans.

30 May 2018

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28 July 2018

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Human primary co-culture angiogenesis assay reveals additive stimulation and different angiogenic properties of VEGF and HGF.

28 November 2018

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Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4.

28 November 2018

1 reference

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Regulation of angiogenesis and endothelial cell motility by matrix-bound fibroblasts

28 November 2018

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Glioblastoma and cerebral microvascular endothelial cell migration in response to tumor-associated growth factors

28 November 2018

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Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

HGF receptor up-regulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs).

28 November 2018

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Hepatocyte growth factor is associated with poor prognosis of malignant gliomas and is a predictor for recurrence of meningioma.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1871724

Smooth muscle-derived factor stimulates mobility of human tumor cells.

28 November 2018

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Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells

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12 December 2020

Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human atherosclerotic plaques

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12 December 2020

Impact of c-Met expression on angiogenesis in soft tissue sarcomas: correlation to microvessel-density

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12 December 2020

Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice

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12 December 2020

Expression of local hepatocyte growth factor system in vascular tissues

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12 December 2020

Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis

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12 December 2020

Angiogenesis and angiogenic growth factors in Wilms tumor

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12 December 2020

Hepatocyte growth factor signaling regulates transactivation of genes belonging to the plasminogen activation system via hypoxia inducible factor-1

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12 December 2020

Coexpression of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor cMET predict recurrence of meningiomas

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12 December 2020

Design and expression of chimeric U1/ribozyme transgenes

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12 December 2020

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression

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12 December 2020

Hepatocyte growth factor modulates vascular endothelial-cadherin expression in human endothelial cells

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12 December 2020

Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells

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12 December 2020

Hepatocyte growth factor upregulates thymosin beta4 in human umbilical vein endothelial cells

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12 December 2020

HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice

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12 December 2020

Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells

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12 December 2020

Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells

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12 December 2020

Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats

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12 December 2020

Tumor angiogenesis, hepatocyte growth factor, and c-Met expression in endometrial carcinoma

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12 December 2020