Th2 cytokines and asthma. Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists (Q24791820)

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English	Th2 cytokines and asthma. Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

21 June 2017

8 references

31 July 2019

3 August 2019

9 August 2019

12 October 2019

18 October 2019

20 November 2019

15 December 2019

25 January 2021

Th2 cytokines and asthma. Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists (English)

1 reference

Europe PubMed Central

21 June 2017

7 references

31 July 2019

3 August 2019

9 August 2019

12 October 2019

18 October 2019

20 November 2019

15 December 2019

1 reference

based on heuristic

inferred from title

0 references

cell surface receptor

1 reference

31 July 2019

lymphocyte subsets

1 reference

3 August 2019

T-lymphocyte subsets

1 reference

9 August 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

20 November 2019

membrane protein

1 reference

15 December 2019

1 reference

25 January 2021

Larry C. Borish

2

object named as

L Borish

1 reference

Europe PubMed Central

21 June 2017

John W. Steinke

1

object named as

J W Steinke

1 reference

Europe PubMed Central

21 June 2017

language of work or name

0 references

publication date

19 February 2001

9 references

Europe PubMed Central

21 June 2017

31 July 2019

3 August 2019

9 August 2019

12 October 2019

18 October 2019

20 November 2019

15 December 2019

25 January 2021

Respiratory Research

9 references

Europe PubMed Central

21 June 2017

31 July 2019

3 August 2019

9 August 2019

12 October 2019

18 October 2019

20 November 2019

15 December 2019

25 January 2021

2

1 reference

Europe PubMed Central

21 June 2017

2

1 reference

Europe PubMed Central

21 June 2017

66-70

1 reference

Europe PubMed Central

21 June 2017

Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

7 April 2017

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

7 April 2017

IL-4/IL-13 signaling beyond JAK/STAT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

7 April 2017

Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 September 2017

Effect of inhaled interleukin-4 on airway hyperreactivity in asthmatics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

30 May 2018

Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

30 May 2018

Genetics of atopy and asthma: the rationale behind promoter-based candidate gene studies (IL-4 and IL-10).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

30 May 2018

Variants of STAT6 (signal transducer and activator of transcription 6) in atopic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 November 2018

Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 November 2018

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59570

28 November 2018

Genetic variants of IL-13 signalling and human asthma and atopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant interleukin (IL)-4 and IL-5 production in vitro by CD4+ helper T cells from atopic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HindIII polymorphism in the BCL6 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 is required for the induction of lung Th2 mucosal immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 and soluble CD23 serum levels in asthmatic atopic children

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal IL-4 gene expression by atopic dermatitis T lymphocytes is reflected in altered nuclear protein interactions with IL-4 transcriptional regulatory element

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal production of T helper 2 cytokines interleukin-4 and interleukin-5 by T cells from newborns with atopic parents

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allergen-induced cytokine production in atopic disease and its relationship to disease severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine rescue from glucocorticoid induced apoptosis in T cells is mediated through inhibition of IkappaBalpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in nasal fluids from school children with seasonal allergic rhinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 and IL-13 specifically increase adhesion molecule and inflammatory cytokine expression in human lung fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble IL-4 receptor inhibits airway inflammation following allergen challenge in a mouse model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11686867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

21 June 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/rr40

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Europe PubMed Central

21 June 2017

ResearchGate publication ID

0 references

Springer Nature article ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/rr40

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