The lung as a route for systemic delivery of therapeutic proteins and peptides (Q24792013)

2

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M Armand

3

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R Kinget

4

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N Verbeke

Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model

5

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language of work or name

English

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publication date

2001

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12 April 2001

2 references

9 October 2019

20 November 2019

2 references

9 October 2019

20 November 2019

2

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issue

4

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page(s)

198-209

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Safety of inhaled proteins for therapeutic use.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Delivery of biotherapeutics by inhalation aerosol.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Systemic delivery of peptides and proteins across absorptive mucosae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Intrapulmonary administration of insulin to healthy volunteers.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Study on pulmonary delivery of salmon calcitonin in rats: effects of protease inhibitors and absorption enhancers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Recent progress in protein and peptide delivery by noninvasive routes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Intra-individual variability of the metabolic effect of inhaled insulin together with an absorption enhancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Novel lipid-based hollow-porous microparticles as a platform for immunoglobulin delivery to the respiratory tract

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

An exploration of intrapulmonary insulin administration in anaesthetized and mechanically ventilated pigs.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Effects of phospholipid chain length, concentration, charge, and vesicle size on pulmonary insulin absorption

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Clinical comparison of inhaled budesonide delivered either via pressurized metered dose inhaler or Turbuhaler

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Pulmonary delivery of peptide drugs: effect of particle size on bioavailability of leuprolide acetate in healthy male volunteers

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

The pharmacokinetics of pulmonary-delivered insulin: a comparison of intratracheal and aerosol administration to the rabbit

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Time to peak insulin level, relative bioavailability, and effect of site of deposition of nebulized insulin in patients with noninsulin-dependent diabetes mellitus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Improvement of the pulmonary absorption of (Asu1,7)-eel calcitonin by various absorption enhancers and their pulmonary toxicity in rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Systemic absorption and activity of recombinant consensus interferons after intratracheal instillation and aerosol administration

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Pulmonary absorption of recombinant methionyl human granulocyte colony stimulating factor (r-huG-CSF) after intratracheal instillation to the hamster

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Insulin across respiratory mucosae by aerosol delivery

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59577

Antiviral and antitumor effects of a human interferon analog, IFN-alpha Con 1, assessed in hamsters

28 November 2018

1 reference

12 December 2020

Permeability of the respiratory tract to different-sized macromolecules after intratracheal instillation in young and adult rats

1 reference

12 December 2020

Lung to blood passage of human growth hormone after intratracheal instillation: stimulation of growth in hypophysectomized rats

1 reference

12 December 2020

Pulmonary biotransformation of insulin in rat and rabbit

1 reference

12 December 2020

Pulmonary effects of chronic exposure to liposome aerosols in mice

1 reference

12 December 2020

Pulmonary delivery of free and liposomal insulin

1 reference

12 December 2020

Lung to blood passage of albumin and a nonapeptide after intratracheal instillation in the young developing pig

1 reference

12 December 2020

Improvement of the pulmonary absorption of (Asu1,7)-eel calcitonin by various protease inhibitors in rats

1 reference

12 December 2020

Pulmonary delivery of detirelix by intratracheal instillation and aerosol inhalation in the briefly anesthetized dog

1 reference

12 December 2020

Pharmacokinetics of detirelix following intratracheal instillation and aerosol inhalation in the unanesthetized awake sheep

1 reference

12 December 2020

Pulmonary delivery of powders and solutions containing recombinant human granulocyte colony-stimulating factor (rhG-CSF) to the rabbit

1 reference

12 December 2020

The influence of regional deposition on the pharmacokinetics of pulmonary-delivered human growth hormone in rabbits

1 reference

12 December 2020

Susceptibility of insulin to proteolysis in rat lung homogenate and its protection from proteolysis by various protease inhibitors

1 reference

12 December 2020

Intratracheal delivery of peptide and protein agents: absorption from solution and dry powder by rat lung

1 reference

12 December 2020

Large porous particles for pulmonary drug delivery

1 reference

12 December 2020

Pulmonary delivery of intratracheally instilled and aerosolized cyclosporine A to young and adult rats

1 reference

12 December 2020

Flow-dependent effect of formoterol dry-powder inhaled from the Aerolizerfi

1 reference

12 December 2020

Is total particle dose more important than particle distribution?

1 reference

12 December 2020

Proteolytic enzymes as a limitation for pulmonary absorption of insulin: in vitro and in vivo investigations

1 reference

12 December 2020

Systemic delivery of the GnRH antagonist cetrorelix by intratracheal instillation in anesthetized rats

1 reference

12 December 2020

Lanthanides enhance pulmonary absorption of insulin

1 reference

12 December 2020

Parenteral absorption of insulin from the lung in diabetic children

1 reference

12 December 2020

Identifiers

DOI

10.1186/RR58

1 reference

Dimensions Publication ID

2304892

1024988230

0 references

2304892

1 reference

1 reference

1 reference