IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways (Q24793443)

2

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Kyoung-Woon Kim

3

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Mi-Kyung Park

4

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Youngmee Moon

5

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Wan-Uk Kim

6

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Ho-Youn Kim

Arthritis Research and Therapy

7

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language of work or name

English

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publication date

2004

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published in

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volume

6

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issue

2

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page(s)

R120-8

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cites work

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Functional analysis of an arthritogenic synovial fibroblast

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Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis

7 April 2017

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A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways

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IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

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IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1

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Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis

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Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction

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A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity

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IL-17: prototype member of an emerging cytokine family

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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Effector function of type II collagen-stimulated T cells from rheumatoid arthritis patients: cross-talk between T cells and synovial fibroblasts

7 April 2017

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Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy

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Effector function of resting T cells: activation of synovial fibroblasts

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Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells

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Interleukin 6 is required for the development of collagen-induced arthritis

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Human native soluble CD40L is a biologically active trimer, processed inside microsomes

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Effect of pro-inflammatory/anti-inflammatory agents on cytokine secretion by peripheral blood mononuclear cells in rheumatoid arthritis and systemic lupus erythematosus.

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Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines.

30 May 2018

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Necessary role of phosphatidylinositol 3-kinase in transforming growth factor beta-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts

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IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts

28 November 2018

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IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators

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Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

28 November 2018

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12 December 2020

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

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12 December 2020

Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17

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12 December 2020

High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

1 reference

12 December 2020

Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun

1 reference

12 December 2020

Cytokine expression and synovial pathology in the initiation and spontaneous resolution phases of adjuvant arthritis: interleukin-17 expression is upregulated in early disease

1 reference

12 December 2020

IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis

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12 December 2020

Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes

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12 December 2020

Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo

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12 December 2020

Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65

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12 December 2020

Heteromultimeric complexes of CD40 ligand are present on the cell surface of human T lymphocytes

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12 December 2020

Identifiers

DOI

10.1186/AR1038

1 reference

Dimensions Publication ID

1036783360

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1 reference

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PubMed publication ID

15059275

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