Why nutraceuticals do not prevent or treat Alzheimer's disease (Q24793469)

Europe PubMed Central

25 April 2019

Europe PubMed Central

on focus list of Wikimedia project

20 August 2019

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copyrighted

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ScienceSource

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https://scigraph.springernature.com/pub.10.1186/1475-2891-4-14

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cites work

Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Heme oxygenase expression in human central nervous system disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Dietary factors and Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Metals in our minds: therapeutic implications for neurodegenerative disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Novel peptoids for the detection and suppression of reactive oxygen and nitrogen species

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Metal complexing agents as therapies for Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Nanoscale biogenic iron oxides and neurodegenerative disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Copper, iron and zinc in Alzheimer's disease senile plaques.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

The hydroxylation of tryptophan.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

30 May 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Elevation of serum copper levels in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Dietary intake of antioxidants and risk of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Antioxidant vitamin intake and risk of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Iron inhibits neurotoxicity induced by trace copper and biological reductants

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-4-14

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087502