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English	No label defined	scientific article

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scholarly article

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Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells (English)

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author name string

John P Wiebe

1

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Michael J Lewis

2

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language of work or name

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publication date

22 March 2003

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3

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1

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9

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https://scigraph.springernature.com/pub.10.1186/1471-2407-3-9

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Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Codon 89 polymorphism in the human 5 alpha-reductase gene in primary breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Characterization of a human 20alpha-hydroxysteroid dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Steroid metabolism in human breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

2 references

https://api.crossref.org/works/10.1186/1471-2407-3-9

22 April 2017

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

22 April 2017

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

7 April 2017

Comparative anatomy of the aldo-keto reductase superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

25 May 2017

The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Phenotypic variation in a family with partial androgen insensitivity syndrome explained by differences in 5alpha dihydrotestosterone availability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Hormonal carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Characterization of 5alpha-reductase gene expression in stroma and epithelium of human prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Molecular cloning of human type 3 3 alpha-hydroxysteroid dehydrogenase that differs from 20 alpha-hydroxysteroid dehydrogenase by seven amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

The molecular genetics of steroid 5 alpha-reductases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Steroid 5 alpha-reductase: two genes/two enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Human prostatic steroid 5 alpha-reductase isoforms--a comparative study of selective inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

The pathogenesis of benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Progesterone Metabolism in Normal Human Endometrium During the Menstrual Cycle and in Endometrial Carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

MCF-7: A human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Steroid Metabolism in the Normal Mammary Gland and in the Dimethylbenzanthracene-Induced Mammary Tumor of Rats*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 September 2017

Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

30 May 2018

Synthesis of the allylic gonadal steroids, 3 alpha-hydroxy-4-pregnen-20-one and 3 alpha-hydroxy-4-androsten-17-one, and of 3 alpha-hydroxy-5 alpha-pregnan-20-one

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

30 May 2018

Progesterone metabolism in T47Dco human breast cancer cells--I. 5 alpha-pregnan-3 beta,6 alpha-diol-20-one is the secreted product.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

30 May 2018

A radioimmunoassay for the regulatory allylic steroid, 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

30 May 2018

Studies on the progesterone receptor content and steroid metabolism in normal and pathological human breast tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

30 May 2018

Synthesis, metabolism and levels of the neuroactive steroid, 3alpha-hydroxy-4-pregnen-20-one (3alphaHP), in rat pituitaries.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Evidence of heterogeneity and quantitative differences of the type 1 5alpha-reductase expression in cultured human skin cells--evidence of its presence in melanocytes.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Kinetic parameters of 5 alpha-reductase activity in stroma and epithelium of normal, hyperplastic, and carcinomatous human prostates.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

The steroid 5alpha-reductase type II TA repeat polymorphism is not associated with risk of breast or ovarian cancer in Australian women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 November 2018

5alpha-reductases in human breast carcinoma: possible modulator of in situ androgenic actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154104

28 November 2018

Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Ligand-Modulated Regulation of Progesterone Receptor Messenger Ribonucleic Acid and Protein in Human Breast Cancer Cell Lines

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Synthesis and characteristics of allylic 4-pregnene-3,20-diols found in gonadal and breast tissues

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Progesterone metabolism by guinea pig intrauterine tissues

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

In vitro metabolism of progesterone in the mammary tumor and the normal mammary gland of GRS/A strain of mice and dependency of some steroid-metabolizing enzyme activities upon ovarian function

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Effect of oophorectomy on progesterone metabolism in DMBA-induced mammary tumours of the rat

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Characterization of progesterone receptors and metabolism of progesterone in the normal and cancerous human mammary gland

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Effect of suramin on the biological activity of the two isoforms of the rat 5 alpha-reductase

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

Multiple steroid metabolic pathways in ZR-75-1 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-3-9

21 January 2018

TA repeat polymorphism of the 5alpha-reductase gene and breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Chinese hamster ovary cell lines expressing human steroid 5 alpha-reductase isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid metabolism and steroid receptors in dimethylbenz(a)anthracene-induced rat mammary tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarities and differences in the ultrastructure of two hormone-dependent and one independent human breast carcinoma grown in athymic nude mice: comparison with the rat DMBA-induced tumor and normal secretory mammocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of cell proliferation: evidence for negative control on estrogen-sensitive T47D human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 4-pregnene and 5alpha-pregnane progesterone metabolites formed in nontumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2407-3-9

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