The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes (Q24797661)

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English	The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes	scientific article

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scholarly article

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The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes (English)

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author name string

Sarah Elliott

1

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Ezra Hays

2

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Michael Mayor

3

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Michael Sporn

4

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Matthew Vincenti

5

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language of work or name

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publication date

2003

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Arthritis Research and Therapy

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5

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5

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R285-91

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Pharmacology of oleanolic acid and ursolic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

7 April 2017

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

1 reference

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7 April 2017

Bcl-3 is an interleukin-1-responsive gene in chondrocytes and synovial fibroblasts that activates transcription of the matrix metalloproteinase 1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 September 2017

Predictors of infection in rheumatoid arthritis

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Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study

1 reference

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28 September 2017

The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 September 2017

Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?

1 reference

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28 September 2017

Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

1 reference

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28 September 2017

Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells.

1 reference

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The role of cytokines and growth factors in cartilage destruction in osteoarthritis and rheumatoid arthritis

1 reference

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28 September 2017

Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 September 2017

The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules

1 reference

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28 September 2017

Using inhibitors of metalloproteinases to treat arthritis. Easier said than done?

1 reference

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28 September 2017

In vivo studies of cartilage regeneration after damage induced by catabolin/interleukin-1.

1 reference

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28 September 2017

A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

30 May 2018

Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 November 2018

Modeling the progression of rheumatoid arthritis: a two-country model to estimate costs and consequences of rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 November 2018

Bullous skin lesions following infliximab infusion in a patient with rheumatoid arthritis

1 reference

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28 November 2018

A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 November 2018

The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

1 reference

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28 November 2018

Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193729

28 November 2018

Targeting interleukin-1 in the treatment of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12932292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13

1 reference

https://pubmed.ncbi.nlm.nih.gov/12932292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The breakdown of collagen by chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12932292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagenase and collagenolytic activity in human osteoarthritic cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12932292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthritic lesions: involvement of three different collagenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12932292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12932292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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