Effects of lornoxicam on the physiology of severe sepsis (Q24801307)

1

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Beyhan Karamanlioğlu

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Onur Koyuncu

4

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Zafer Pamukçu

The analgesic NSAID lornoxicam inhibits cyclooxygenase (COX)-1/-2, inducible nitric oxide synthase (iNOS), and the formation of interleukin (IL)-6 in vitro

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language of work or name

English

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publication date

December 2004

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published in

Critical Care

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volume

8

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issue

6

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page(s)

R474-82

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cites work

1 reference

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The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine

7 April 2017

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Is prostacyclin responsible for producing the hyperdynamic response during early sepsis?

7 April 2017

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Basic biology and clinical application of specific cyclooxygenase-2 inhibitors

28 September 2017

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Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group

28 September 2017

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Specific COX-2 inhibitors in arthritis, oncology, and beyond: where is the science headed?

28 September 2017

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The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group

28 September 2017

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Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

28 September 2017

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The pathogenesis of sepsis. Factors that modulate the response to gram-negative bacterial infection

28 September 2017

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Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions

28 September 2017

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Gram-negative sepsis: a dilemma of modern medicine

28 September 2017

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Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2.

28 September 2017

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Arachidonic acid metabolism. Implications of biological chemistry for lung function and disease

28 September 2017

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Outcome of specific COX-2 inhibition in rheumatoid arthritis.

28 September 2017

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Hemodynamic evaluation of ibuprofen in canine hypovolemic shock

30 May 2018

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Lornoxicam, a new potent NSAID with an improved tolerability profile

30 May 2018

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T-cell proliferative responses following sepsis in neonatal rats.

28 November 2018

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Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis

28 November 2018

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Selective inhibition of COX-2 improves early survival in murine endotoxemia but not in bacterial peritonitis

28 November 2018

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The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock.

28 November 2018

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Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production

28 November 2018

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Blocking prostaglandin E2 after trauma attenuates pro-inflammatory cytokines and improves survival

28 November 2018

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12 December 2020

The Complex Pattern of Cytokines in Sepsis Association Between Prostaglandins, Cachectin, and Interleukins

1 reference

12 December 2020

Prostaglandins and sepsis: still a fascinating topic despite almost 40 years of research

1 reference

12 December 2020

Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects

1 reference

12 December 2020

Prostacyclin and thromboxane A2 formation is increased in human sepsis syndrome. Effects of cyclooxygenase inhibition

1 reference

12 December 2020

Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition

1 reference

12 December 2020

Cyclooxygenase inhibition and vascular reactivity in a rat model of hyperdynamic sepsis

1 reference

12 December 2020

Cyclooxygenase-2 inhibitor NS-398 improves survival and restores leukocyte counts in burn infection

1 reference

12 December 2020

Blockade of prostaglandin products augments macrophage and neutrophil tumor necrosis factor synthesis in burn injury

1 reference

12 December 2020

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis

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12 December 2020

Identifiers

DOI

10.1186/CC2969

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Dimensions Publication ID

3169812

1033821389

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3169812

1 reference

1 reference

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