Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model (Q24805875)

2

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Jian-Ping Wang

3

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Maureen F Maughan

4

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John M Polo

5

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Lawrence B Lachman

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

6

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language of work or name

English

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publication date

2004

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published in

Breast Cancer Research

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volume

6

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issue

4

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page(s)

R275-83

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cites work

1 reference

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IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

28 September 2017

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Nonredundant roles of antibody, cytokines, and perforin in the eradication of established Her-2/neu carcinomas

28 September 2017

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28 September 2017

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Growth factor receptors in breast cancer: potential for therapeutic intervention.

28 September 2017

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T cell response to human papillomavirus 16 E7 in mice: comparison of Cr release assay, intracellular IFN-gamma production, ELISPOT and tetramer staining

28 September 2017

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Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

28 September 2017

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

28 September 2017

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Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug

28 September 2017

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Adaptive immunity cooperates with liposomal all-trans-retinoic acid (ATRA) to facilitate long-term molecular remissions in mice with acute promyelocytic leukemia

28 September 2017

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Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group

28 September 2017

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The potential of DNA vaccination against tumor-associated antigens for antitumor therapy

28 September 2017

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Trastuzumab: hopes and realities

28 September 2017

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Cancer vaccines targeting the HER2/neu oncogenic protein

28 September 2017

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Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes.

28 September 2017

1 reference

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DNA vaccination against neu reduces breast cancer incidence and metastasis in mice

28 September 2017

1 reference

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Chemotherapy: friend or foe to cancer vaccines?

28 September 2017

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Immunomodulation by anticancer chemotherapy: more is not always better (review).

28 September 2017

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Examination of CD8+ T cell function in humans using MHC class I tetramers: similar cytotoxicity but variable proliferation and cytokine production among different clonal CD8+ T cells specific to a single viral epitope

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Failure of cancer vaccines: the significant limitations of this approach to immunotherapy

28 September 2017

1 reference

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A HER2/NEU-derived peptide, a K(d)-restricted murine tumor rejection antigen, induces HER2-specific HLA-A2402-restricted CD8(+) cytotoxic T lymphocytes

28 September 2017

1 reference

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Adjuvant therapy for breast cancer

28 September 2017

1 reference

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DNA vaccines encoding full-length or truncated Neu induce protective immunity against Neu-expressing mammary tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo

28 September 2017

1 reference

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B7-1-transfected tumor vaccine counteracts chemotherapy-induced immunosuppression and prolongs the survival of rats bearing highly metastatic osteosarcoma cells

28 September 2017

1 reference

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Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer.

28 September 2017

1 reference

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Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines

28 September 2017

1 reference

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Heterogeneity of the interaction of anticancer agents with the immune system and its possible relevance in chemoimmunotherapy

28 September 2017

1 reference

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Oxazaphosphorines as biological response modifiers--experimental and clinical perspectives

28 September 2017

1 reference

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Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene

28 September 2017

1 reference

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Adriamycin-induced modulation of host defenses in tumor-bearing mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Increased primary cell-mediated immunity in culture subsequent to adriamycin or daunorubicin treatment of spleen donor mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Comparative studies of taxol and taxotere on tumor growth and lymphocyte functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Complementary antitumor immunity induced by plasmid DNA encoding secreted and cytoplasmic human ErbB-2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

DNA vaccination with full-length or truncated neu induces protective immunity against the development of spontaneous mammary tumors in HER-2/neu transgenic mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Rapid on/off cycling of cytokine production by virus-specific CD8+ T cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Correlation between adriamycin-induced augmentation of interleukin 2 production and of cell-mediated cytotoxicity in mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Increase in the effectiveness of melphalan therapy with progression of MOPC-315 plasmacytoma tumor growth.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice.

30 May 2018

1 reference

PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia.

21 January 2018

1 reference

Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing

21 January 2018

1 reference

Prime boost vaccines power up in people.

21 January 2018

1 reference

Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

21 January 2018

1 reference

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=468620

Treatment of breast cancer

28 November 2018

1 reference

c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer

21 January 2018

1 reference

Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma

21 January 2018

1 reference

21 January 2018

1 reference

Vaccination with Her-2/neu DNA or protein subunits protects against growth of a Her-2/neu-expressing murine tumor

21 January 2018

1 reference

Low-dose melphalan-induced shift in the production of a Th2-type cytokine to a Th1-type cytokine in mice bearing a large MOPC-315 tumor

21 January 2018

1 reference

The improved effects of specific active immunotherapy on a rat fibrosarcoma by antitumor drugs

21 January 2018

1 reference

Cancer vaccine targets leukemia

21 January 2018

1 reference

How to "spot" a real killer

21 January 2018

1 reference

Overexpression of c-erbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms

21 January 2018

1 reference

12 December 2020

Generation of immunity to the HER-2/neu oncogenic protein in patients with breast and ovarian cancer using a peptide-based vaccine

1 reference

12 December 2020

Immunomodulatory properties of antineoplastic drugs administered in conjunction with GM-CSF-secreting cancer cell vaccines

1 reference

12 December 2020

Importance of timing in cyclophosphamide therapy of MOPC-315 tumor-bearing mice

1 reference

12 December 2020

Augmentation of the development of immune responses of mice against allogeneic tumor cells after adriamycin treatment

1 reference

12 December 2020

Synergy between low-dose chemotherapy and immunotherapy in mouse L1210 leukemia

1 reference

12 December 2020