N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts (Q24805889)

2

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B F Pachkowski

3

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J Nakamura

4

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M R Kelley

Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

5

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language of work or name

English

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publication date

2005

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published in

Nucleic Acids Research

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volume

33

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issue

9

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page(s)

2859-67

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cites work

1 reference

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3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins

7 April 2017

1 reference

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Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine

7 April 2017

1 reference

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1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase)

7 April 2017

1 reference

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Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases

7 April 2017

1 reference

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Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells

7 April 2017

1 reference

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Mammalian DNA single-strand break repair: an X-ra(y)ted affair

28 September 2017

1 reference

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Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase

28 September 2017

1 reference

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Base excision repair of DNA in mammalian cells

28 September 2017

1 reference

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A simple method for the rapid generation of recombinant adenovirus vectors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome

28 September 2017

1 reference

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The effects of N7-methylguanine on duplex DNA structure

28 September 2017

1 reference

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Cisplatin and DNA repair in cancer chemotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase

28 September 2017

1 reference

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Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Evidence for the simultaneous expression of alternatively spliced alkylpurine N-glycosylase transcripts in human tissues and cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

3-Methyladenine residues in DNA induce the SOS function sfiA in Escherichia coli

28 September 2017

1 reference

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7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Heterogeneous repair of N-methylpurines at the nucleotide level in normal human cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

The chloroethylnitrosoureas: sensitivity and resistance to cancer chemotherapy at the molecular level

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Termination of DNA synthesis in vitro at apurinic sites but not at ethyl adducts on the template.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Alkylation resistance of E. coli cells expressing different isoforms of human alkyladenine DNA glycosylase (hAAG).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Evidence in Escherichia coli that N3-methyladenine lesions induced by a minor groove binding methyl sulfonate ester can be processed by both base and nucleotide excision repair

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Increased resistance to N,N',N"-triethylenethiophosphoramide (thiotepa) in cells expressing the Escherichia coli formamidopyrimidine-DNA glycosylase.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131935

Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent

28 November 2018

1 reference

12 December 2020

Removal of minor methylation products 7-methyladenine and 3-methylguanine from DNA of Escherichia coli treated with dimethyl sulphate

1 reference

12 December 2020

Methylation-induced blocks to in vitro DNA replication

1 reference

12 December 2020

Liquid chromatography-thermospray mass spectrometry of DNA adducts formed with mitomycin C, porfiromycin and thiotepa

1 reference

12 December 2020

Groove- and sequence-selective alkylation of DNA by sulfonate esters tethered to lexitropsins

1 reference

12 December 2020

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

1 reference

12 December 2020

The in vitro methylation of DNA by a minor groove binding methyl sulfonate ester

1 reference

12 December 2020

DNA adducts and the mechanism of carcinogenesis and cytotoxicity of methylating agents of environmental and clinical significance

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKI601

1 reference

release_gaohawlvnzblha75fyh46miswi

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gaohawlvnzblha75fyh46miswi

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

15905475

1 reference