TATA-box binding protein (Q2480972)

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mammalian protein found in Homo sapiens
  • TATA-box-binding protein
  • TATA sequence-binding protein
  • TATA-binding factor
  • TBP
  • transcription initiation factor TFIID TBP subunit
  • TATA-box factor
  • TATA-box binding protein N-terminal domain
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Language Label Description Also known as
English
TATA-box binding protein
mammalian protein found in Homo sapiens
  • TATA-box-binding protein
  • TATA sequence-binding protein
  • TATA-binding factor
  • TBP
  • transcription initiation factor TFIID TBP subunit
  • TATA-box factor
  • TATA-box binding protein N-terminal domain

Statements

molecular function
transcription factor binding
determination method
IPI
5 references
retrieved
16 July 2018
stated in
Potential targets for HSF1 within the preinitiation complex
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
16 July 2018
stated in
TAF7 (TAFII55) plays a role in the transcription activation by c-Jun
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
16 July 2018
stated in
The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
16 July 2018
stated in
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
16 July 2018
stated in
Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IPI
protein binding
determination method
IPI
35 references
retrieved
8 April 2019
stated in
Structural basis of preinitiation complex assembly on human pol II promoters
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of functional domains of an embryonic stem cell coactivator UTF1 which are conserved and essential for potentiation of ATF-2 activity
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Exon 4-encoded acidic domain in the epithelium-restricted Ets factor, ESX, confers potent transactivating capacity and binds to TATA-binding protein (TBP)
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Wild-type p53 binds to the TATA-binding protein and represses transcription
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Specific interactions and potential functions of human TAFII100
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The role of human MBF1 as a transcriptional coactivator
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The equine herpesvirus 1 EICP27 protein enhances gene expression via an interaction with TATA box-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Identification of novel functional TBP-binding sites and general factor repertoires
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Histone-like TAFs within the PCAF histone acetylase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The EHV-1 UL4 protein that tempers viral gene expression interacts with cellular transcription factors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The unique IR2 protein of equine herpesvirus 1 negatively regulates viral gene expression
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteins
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The equine herpesvirus 1 EICP27 protein enhances gene expression via an interaction with TATA box-binding protein
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The EHV-1 UL4 protein that tempers viral gene expression interacts with cellular transcription factors
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
transcription factor binding
determination method
IBA
IPI
6 references
retrieved
8 April 2019
stated in
Potential targets for HSF1 within the preinitiation complex
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
TAF7 (TAFII55) plays a role in the transcription activation by c-Jun
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IBA
cell component
transcription factor TFIID complex
determination method
IDA
IEA
TAS
6 references
retrieved
16 July 2018
stated in
Functional domains and upstream activation properties of cloned human TATA binding protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IEA
retrieved
16 July 2018
stated in
Near-atomic resolution visualization of human transcription promoter opening
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
16 July 2018
stated in
Structure of promoter-bound TFIID and model of human pre-initiation complex assembly
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
16 July 2018
stated in
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
16 July 2018
stated in
The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IDA
transcription factor TFIID complex
determination method
IBA
IDA
IEA
TAS
7 references
retrieved
8 April 2019
stated in
Functional domains and upstream activation properties of cloned human TATA binding protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IEA
retrieved
8 April 2019
stated in
Structure of promoter-bound TFIID and model of human pre-initiation complex assembly
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
8 April 2019
stated in
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
8 April 2019
stated in
Near-atomic resolution visualization of human transcription promoter opening
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
8 April 2019
stated in
The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IBA
biological process
transcription by RNA polymerase II
determination method
IC
IDA
IEA
IMP
TAS
7 references
retrieved
16 July 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
16 July 2018
stated in
Cloning of a transcriptionally active human TATA binding factor
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
16 July 2018
stated in
Functional domains and upstream activation properties of cloned human TATA binding protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
16 July 2018
stated in
Near-atomic resolution visualization of human transcription promoter opening
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IMP
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IEA
retrieved
16 July 2018
stated in
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
16 July 2018
stated in
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20226&geneProductId=UniProtKB:P20226
determination method
IC
transcription by RNA polymerase II
determination method
IBA
IC
IDA
IEA
IMP
TAS
8 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
8 April 2019
stated in
Cloning of a transcriptionally active human TATA binding factor
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
8 April 2019
stated in
Functional domains and upstream activation properties of cloned human TATA binding protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
TAS
retrieved
8 April 2019
stated in
Near-atomic resolution visualization of human transcription promoter opening
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IEA
retrieved
8 April 2019
stated in
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IDA
retrieved
8 April 2019
stated in
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
GOA
curator
UniProt
UniProt protein ID
P20226
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IC
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20226
determination method
IBA
Gene Atlas image
PBB GE TBP 203135 at fs.png
732 × 530; 12 KB
0 references

Identifiers

PDB structure ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q2480972&oldid=2022903855"