Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration (Q24812224)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16262900%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration (English)

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microvasculature remodeling

8 January 2020

main subject

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inferred from title

author

Soni Savai Pullamsetti

1

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8 January 2020

Ardeschir Ghofrani

4

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8 January 2020

Norbert Weissmann

6

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8 January 2020

Werner Seeger

8

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8 January 2020

Friedrich Grimminger

9

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8 January 2020

Ralph T Schermuly

10

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8 January 2020

5

Christian Schudt

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8 January 2020

2

Stefanie Krick

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8 January 2020

7

Beate Fuchs

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8 January 2020

author name string

Hüseyin Yilmaz

3

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8 January 2020

language of work or name

English

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publication date

1 November 2005

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8 January 2020

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8 January 2020

volume

6

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8 January 2020

issue

1

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page(s)

128

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Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells

8 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Cellular pathophysiology and therapy of pulmonary hypertension.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Physiologic basis for the treatment of pulmonary hypertension.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Primary pulmonary hypertension: a vascular biology and translational research "Work in progress".

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Elevation of intracellular cAMP inhibits growth factor-mediated matrix metalloproteinase-9 induction and keratinocyte migration.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Real-time quantitative RT-PCR after laser-assisted cell picking

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Ultrasonic nebulization for efficient delivery of surfactant in a model of acute lung injury. Impact on gas exchange

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Diversity in cyclic nucleotide phosphodiesterase isoenzyme families

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Pressure-induced connective tissue synthesis in pulmonary artery segments is dependent on intact endothelium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Activation and pulmonary toxicity of pyrrolizidine alkaloids

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Investigational Approaches to Pulmonary Hypertension*1,2

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension

30 May 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Efficacy, safety and tolerability of duloxetine 60 mg once daily in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Suppressive effect of pulmonary hypertension and leukocyte activation by inhaled prostaglandin E1 in rats with monocrotaline-induced pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Repeated inhalation of adrenomedullin ameliorates pulmonary hypertension and survival in monocrotaline rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Participation of PI3K and ERK1/2 pathways are required for human brain vascular smooth muscle cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Inhibition of the NF-kappaB transcriptional activity by protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element 'decoy' of nuclear factor-kappaB binding site as a novel molecular strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-6-128

All-trans retinoic acid in pulmonary vascular structural remodeling in rats with pulmonary hypertension induced by monocrotaline.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1291406

Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor

28 November 2018

1 reference

12 December 2020

Prostacyclin Analogues Differentially Inhibit Growth of Distal and Proximal Human Pulmonary Artery Smooth Muscle Cells

1 reference

12 December 2020

Injury induces dedifferentiation of smooth muscle cells and increased matrix-degrading metalloproteinase activity in human saphenous vein

1 reference

12 December 2020

Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation

1 reference

12 December 2020

Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat

1 reference

12 December 2020

Adrenomedullin as a novel antimigration factor of vascular smooth muscle cells

1 reference

12 December 2020

In vivo collagen turnover following experimental balloon angioplasty injury and the role of matrix metalloproteinases

1 reference

12 December 2020

Migration of vascular smooth muscle cells is enhanced in cultures derived from spontaneously hypertensive rat

1 reference

12 December 2020

cAMP involvement in the expression of MMP-2 and MT-MMP1 metalloproteinases in human endothelial cells

1 reference

12 December 2020

The effect of bosentan on matrix metalloproteinase-9 levels in patients with systemic sclerosis-induced pulmonary hypertension

1 reference

12 December 2020

Low-dose Systemic Phosphodiesterase Inhibitors Amplify the Pulmonary Vasodilatory Response to Inhaled Prostacyclin in Experimental Pulmonary Hypertension

1 reference

12 December 2020

Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange

1 reference

12 December 2020

Identifiers

DOI

10.1186/1465-9921-6-128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16262900%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 January 2020

1 reference

https://scigraph.springernature.com/pub.10.1186/1465-9921-6-128

9 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16262900%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference