The influence of locked nucleic acid residues on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexes (Q24812616)

5

object named as

Douglas H Turner

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Elzbieta Kierzek

1

object named as

Elzbieta Kierzek

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author name string

Anna Ciesielska

2

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Karol Pasternak

3

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David H Mathews

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

4

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language of work or name

English

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publication date

2005

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published in

Nucleic Acids Research

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volume

33

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issue

16

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page(s)

5082-93

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cites work

1 reference

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Secondary structure and hybridization accessibility of hepatitis C virus 3'-terminal sequences

7 April 2017

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Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids

7 April 2017

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The 1.19 A X-ray structure of 2'-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove

7 April 2017

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Investigation of the structural basis for thermodynamic stabilities of tandem GU mismatches: solution structure of (rGAGGUCUC)2 by two-dimensional NMR and simulated annealing

7 April 2017

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Asymmetry in the assembly of the RNAi enzyme complex

7 April 2017

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Quantitative monitoring of gene expression patterns with a complementary DNA microarray

7 April 2017

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The thermodynamics of DNA structural motifs

7 April 2017

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In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotide

7 April 2017

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Molecular interactions on microarrays

7 April 2017

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Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

7 April 2017

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Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs

7 April 2017

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Improved Estimation of Secondary Structure in Ribonucleic Acids

7 April 2017

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From genes to machines: DNA nanomechanical devices

7 April 2017

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Building programmable jigsaw puzzles with RNA.

28 September 2017

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LNA-antisense rivals siRNA for gene silencing

28 September 2017

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LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.

28 September 2017

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Gold nanoparticle probe-based gene expression analysis with unamplified total human RNA.

28 September 2017

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Label-free colorimetric detection of specific sequences in genomic DNA amplified by the polymerase chain reaction

28 September 2017

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Rational design of DNA sequences for nanotechnology, microarrays and molecular computers using Eulerian graphs

28 September 2017

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Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology.

28 September 2017

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Structural analysis of hepatitis C RNA genome using DNA microarrays

28 September 2017

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The peptide nucleic acids (PNAs), powerful tools for molecular genetics and cytogenetics

28 September 2017

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Oligonucleotide microarrays in microbial diagnostics

28 September 2017

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Oligonucleotide therapeutics: 25 years agrowing

28 September 2017

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The peptide nucleic acids, efficient tools for molecular diagnosis (Review).

28 September 2017

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Efficient RNA interference depends on global context of the target sequence: quantitative analysis of silencing efficiency using Eulerian graph representation of siRNA.

28 September 2017

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Probing alternative foldings of the HIV-1 leader RNA by antisense oligonucleotide scanning arrays

28 September 2017

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Nucleic acid nanotechnology-towards Angstrom-scale engineering.

28 September 2017

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Probe selection for high-density oligonucleotide arrays

28 September 2017

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Thermodynamic criteria for high hit rate antisense oligonucleotide design

28 September 2017

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Thermodynamic calculations and statistical correlations for oligo-probes design.

28 September 2017

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Real-time PCR technology for cancer diagnostics.

28 September 2017

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Design of antisense oligonucleotides stabilized by locked nucleic acids

28 September 2017

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2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug

28 September 2017

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Effect of secondary structure on the thermodynamics and kinetics of PNA hybridization to DNA hairpins.

28 September 2017

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Synthetic oligonucleotides as RNA mimetics: 2'-modified Rnas and N3'-->P5' phosphoramidates

28 September 2017

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Derivation of nearest-neighbor properties from data on nucleic acid oligomers. II. Thermodynamic parameters of DNA.RNA hybrids and DNA duplexes

28 September 2017

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Derivation of nearest-neighbor properties from data on nucleic acid oligomers. I. Simple sets of independent sequences and the influence of absent nearest neighbors

28 September 2017

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Oligonucleotide N3'-->P5' phosphoramidates as potential therapeutic agents

28 September 2017

1 reference

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RNA mimetics: oligoribonucleotide N3'-->P5' phosphoramidates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201327

Antisense binding enhanced by tertiary interactions: binding of phosphorothioate and N3'-->P5' phosphoramidate hexanucleotides to the catalytic core of a group I ribozyme from the mammalian pathogen Pneumocystis carinii

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201327

Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201327

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201327

Parallel human genome analysis: microarray-based expression monitoring of 1000 genes

28 September 2017

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Current concepts in antisense drug design

28 September 2017

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Complementary Oligonucleotide Binding to the Anticodon Loop of fMet-transfer RNA

28 September 2017

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Stability of ribonucleic acid double-stranded helices

28 September 2017

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28 September 2017

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28 September 2017

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How to find all those mutations

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12 December 2020

Nucleotides LXIV[1]: synthesis hydridization and enzymatic degradation studies of 2'-O-methyloligoribonucleotides and 2'-O-methyl/deoxy gapmers

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Identifiers

DOI

10.1093/NAR/GKI789

1 reference

1 reference

1 reference

PubMed publication ID

16155181

1 reference