Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agent (Q24817148)

5 July 2017

title

Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agent (English)

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5 July 2017

1 reference

Jayati Roy Choudhury

1

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5 July 2017

Ulrich Bierbach

series ordinal

2

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5 July 2017

language of work or name

English

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publication date

28 September 2005

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5 July 2017

published in

Nucleic Acids Research

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5 July 2017

volume

33

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5 July 2017

issue

17

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5 July 2017

page(s)

5622-5632

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TATA element recognition by the TATA box-binding protein has been conserved throughout evolution

5 July 2017

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Solution structure of a complex between [N-MeCys3,N-MeCys7]TANDEM and [d(GATATC)]2

7 April 2017

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Solution structure of a quinomycin bisintercalator-DNA complex

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7 April 2017

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A non-crosslinking platinum-acridine hybrid agent shows enhanced cytotoxicity compared to clinical BCNU and cisplatin in glioblastoma cells.

28 September 2017

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Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin

28 September 2017

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Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity.

28 September 2017

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Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer

28 September 2017

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Bisintercalating threading diacridines: relationships between DNA binding, cytotoxicity, and cell cycle arrest

28 September 2017

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Hairpin-duplex equilibrium reflected in the A-->B transition in an undecamer quasi-palindrome present in the locus control region of the human beta-globin gene cluster

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Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate

28 September 2017

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Site selective bis-intercalation of a homodimeric thiazole orange dye in DNA oligonucleotides

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28 September 2017

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DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

28 September 2017

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The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

28 September 2017

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Circular dichroism spectroscopy of DNA

28 September 2017

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DNA polyintercalating drugs: DNA binding of diacridine derivatives

28 September 2017

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DNA bifunctional intercalators. 1. Synthesis and conformational properties of an ethidium homodimer and of an acridine ethidium heterodimer

28 September 2017

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Stacking interactions and intercalative DNA binding

28 September 2017

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Optical absorbance and fluorescence techniques for measuring DNA-drug interactions

31 May 2018

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Sequence-selective intercalation of antitumour bis-naphthalimides into DNA. Evidence for an approach via the major groove

31 May 2018

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Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.

31 May 2018

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Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening.

31 May 2018

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Equilibrium constants for the binding of an homologous series of monofunctional and bifunctional intercalating diacridines to calf thymus DNA

31 May 2018

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DNA Bifunctional intercalators. 2. Fluorescence properties and DNA binding interaction of an ethidium homodimer and an acridine ethidium heterodimer

31 May 2018

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DNA minor groove adducts formed by a platinum-acridine conjugate inhibit association of tata-binding protein with its cognate sequence

31 May 2018

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Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent

28 November 2018

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Duplex-promoted platination of adenine-N3 in the minor groove of DNA: challenging a longstanding bioinorganic paradigm

28 November 2018

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Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug

28 November 2018

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Design of a sequence-specific DNA bisintercalator

28 November 2018

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Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent

28 November 2018

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Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent

28 November 2018

1 reference

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Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents

28 November 2018

1 reference

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Bis(acridinylthiourea)platinum(II) complexes: synthesis, DNA affinity, and biological activity in glioblastoma cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236979

Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236979

Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore

28 November 2018

1 reference

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Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring.

28 November 2018

1 reference

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Improved nearest-neighbor parameters for predicting DNA duplex stability

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16192574

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKI869

1 reference

5 July 2017

1 reference

5 July 2017

1 reference