The P450 CYP6Z1 confers carbamate/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation (Q26314467)

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English	The P450 CYP6Z1 confers carbamate/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation	scientific article

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3 April 2020

The P450 CYP6Z1 confers carbamate/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation (English)

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3 April 2020

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Sulaiman S Ibrahim

1

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3 April 2020

Charles S. Wondji

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author name string

Miranda Ndula

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Jacob M Riveron

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Helen Irving

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15 June 2016

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Molecular Ecology

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3436-3452

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14

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3 April 2020

Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids

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Comparative molecular modeling of Anopheles gambiae CYP6Z1, a mosquito P450 capable of metabolizing DDT

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A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector

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High level of pyrethroid resistance in an Anopheles funestus population of the Chokwe District in Mozambique

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Development and validation of a genetic algorithm for flexible docking

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CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

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Allelic Variation of Cytochrome P450s Drives Resistance to Bednet Insecticides in a Major Malaria Vector

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Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms.

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28 September 2017

The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa

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Country-level operational implementation of the Global Plan for Insecticide Resistance Management

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Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso

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Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus.

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Impact of pyrethroid resistance on operational malaria control in Malawi

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Pinpointing P450s associated with pyrethroid metabolism in the dengue vector, Aedes aegypti: developing new tools to combat insecticide resistance

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Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed

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A comparative study of the CYP450 inhibition potential of marketed drugs using two fluorescence based assay platforms routinely used in the pharmaceutical industry

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Pyrethroid resistance in southern African Anopheles funestus extends to Likoma Island in Lake Malawi

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De novo transcriptome sequencing in Anopheles funestus using Illumina RNA-seq technology

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Cuticle thickening associated with pyrethroid resistance in the major malaria vector Anopheles funestus

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Costs of insensitive acetylcholinesterase insecticide resistance for the malaria vector Anopheles gambiae homozygous for the G119S mutation

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Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector

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Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria

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Molecular basis of resistance to azole antifungals

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Characterization of inhibitors and substrates of Anopheles gambiae CYP6Z2.

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An amino acid substitution attributable to insecticide-insensitivity of acetylcholinesterase in a Japanese encephalitis vector mosquito, Culex tritaeniorhynchus

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10.1111/MEC.13673

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