Inhibition of RNA Helicases of ssRNA(+) Virus Belonging to Flaviviridae, Coronaviridae and Picornaviridae Families (Q26700087)

International journal of medicinal chemistry

Europe PubMed Central

title

Inhibition of RNA Helicases of ssRNA(+) Virus Belonging to Flaviviridae, Coronaviridae and Picornaviridae Families (English)

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Coronaviridae

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Picornaviridae

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Irene Briguglio

1

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Sandra Piras

series ordinal

2

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Paola Corona

series ordinal

3

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Antonio Carta

series ordinal

4

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language of work or name

English

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publication date

2011

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published in

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Creative Commons Attribution 3.0 Unported

volume

2011

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page(s)

213135

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copyright license

start time

16 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

2 references

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Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

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NS3 Peptide, a Novel Potent Hepatitis C Virus NS3 Helicase Inhibitor: Its Mechanism of Action and Antiviral Activity in the Replicon System

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Characterization of imidazo[4,5-d]pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme

7 April 2017

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Crystal structure of a DExx box DNA helicase

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Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

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The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes

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Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function

7 April 2017

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Loading Rho to terminate transcription

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Synthesis of new acridone derivatives, inhibitors of NS3 helicase, which efficiently and specifically inhibit subgenomic HCV replication

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Discovery of a novel HCV helicase inhibitor by a de novo drug design approach

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Present perspectives on flaviviral chemotherapy

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Synthesis and anti-picornaviridae in vitro activity of a new class of helicase inhibitors the N,N'-bis[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl] alkyldicarboxamides

28 September 2017

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Helicases as antiviral and anticancer drug targets

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28 September 2017

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28 September 2017

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31 May 2018

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Helicase inhibition by anthracycline anticancer agents

31 May 2018

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31 May 2018

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The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA.

31 May 2018

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New anti-HSV therapeutics target the helicase-primase complex

21 January 2018

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Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses

21 January 2018

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Ring-expanded ("fat") nucleoside and nucleotide analogues exhibit potent in vitro activity against flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus

21 January 2018

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21 January 2018

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Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ("fat") nucleoside analogues

21 January 2018

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Viral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of the enzyme (motif VI).

21 January 2018

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Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663.

21 January 2018

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21 January 2018

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21 January 2018

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Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor

21 January 2018

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21 January 2018

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Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture

21 January 2018

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21 January 2018

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21 January 2018

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A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses

21 January 2018

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Epidemiology of Hepatocellular Carcinoma

21 January 2018

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21 January 2018

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