The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification (Q26740003)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547766%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Chartrisa LaShan Simpson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547766%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

James A Stewart

3

1 reference

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12 June 2020

author name string

Amber M Kay

1

0 references

C LaShan Simpson

2

0 references

James A Stewart

Journal of Diabetes Research

3

0 references

language of work or name

English

0 references

publication date

28 July 2016

8 references

13 March 2019

14 March 2019

24 March 2019

31 July 2019

15 December 2019

21 December 2019

4 February 2021

20 October 2022

10 references

13 March 2019

14 March 2019

24 March 2019

31 July 2019

15 December 2019

21 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547766%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

4 February 2021

20 October 2022

2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547766%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

6809703

1 reference

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Creative Commons Attribution 4.0 International

12 June 2020

copyright license

8 references

13 March 2019

14 March 2019

24 March 2019

31 July 2019

15 December 2019

21 December 2019

4 February 2021

on focus list of Wikimedia project

20 October 2022

copyright status

copyrighted

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ScienceSource

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cites work

The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Vascular calcification: pathobiology of a multifaceted disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

7 April 2017

https://api.crossref.org/works/10.1155/2016/6809703

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

A multicellular signal transduction network of AGE/RAGE signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Advanced glycation end-products enhance calcification in vascular smooth muscle cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

The serum protein alpha2-HS glycoprotein/fetuin inhibits apatite formation in vitro and in mineralizing calvaria cells. A possible role in mineralization and calcium homeostasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Oxidative Stress and Diabetic Complications

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

AGE-RAGE signal generates a specific NF-κB RelA "barcode" that directs collagen I expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Type 2 diabetes mellitus: From a metabolic disorder to an inflammatory condition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Vascular effects of advanced glycation end-products: content of immunohistochemically detected AGEs in radial artery samples as a predictor for arterial calcification and cardiovascular risk in asymptomatic patients with chronic kidney disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

A current understanding of vascular calcification in CKD.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Reduction of advanced-glycation end products levels and inhibition of RAGE signaling decreases rat vascular calcification induced by diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Vascular calcification: an update on mechanisms and challenges in treatment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

The role of osteocalcin in human glucose metabolism: marker or mediator?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Role of fetuin-A in atherosclerosis associated with diabetic patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Anti-inflammatory role of fetuin-A in injury and infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Serum fetuin-A associates with type 2 diabetes and insulin resistance in Chinese adults

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Oxidative stress, insulin signaling, and diabetes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Activation of protein kinase C isoforms and its impact on diabetic complications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

The mechanism of mineralization and the role of alkaline phosphatase in health and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Plasma fetuin-A levels and the risk of type 2 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Mechanisms of vascular calcification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Vascular calcification: pathobiological mechanisms and clinical implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Advanced glycation end products: sparking the development of diabetic vascular injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Bone morphogenetic proteins in vascular calcification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Vascular calcification mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Hyperglycaemia and cardiovascular risk.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Activation of p38 Mitogen-Activated Protein Kinase Is Required for Osteoblast Differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

High glucose-induced activation of protein kinase signaling pathways in vascular smooth muscle cells: a potential role in the pathogenesis of vascular dysfunction in diabetes (review).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Advanced glycation end-products: a review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Transforming growth factor beta signaling mediators and modulators

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Protein kinase C activation and the development of diabetic complications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Nucleation of hydroxyapatite by bone sialoprotein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Bone matrix mRNA expression in differentiating fetal bovine osteoblasts

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980539

Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers.

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

How does bone sialoprotein promote the nucleation of hydroxyapatite? A molecular dynamics study using model peptides of different conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Hyperglycemia-induced alteration of vascular smooth muscle phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Enhanced expression of osteopontin by high glucose in cultured rat aortic smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

Advanced glycation end products in vitreous: Structural and functional implications for diabetic vitreopathy

21 January 2018

1 reference

12 December 2020

Enhanced expression of osteopontin in human diabetic artery and analysis of its functional role in accelerated atherogenesis

1 reference

12 December 2020

Activation of receptor for advanced glycation end products induces osteogenic differentiation of vascular smooth muscle cells

1 reference

12 December 2020

Association of fetuin-A and cardiac calcification and inflammation levels in hemodialysis patients

1 reference

12 December 2020

Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies

1 reference

12 December 2020

Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease

1 reference

12 December 2020

Role of calcification inhibitors in the pathogenesis of vascular calcification in chronic kidney disease (CKD)

1 reference

12 December 2020

High glucose increases the expression of Cbfa1 and BMP-2 and enhances the calcification of vascular smooth muscle cells

1 reference

12 December 2020

Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization

1 reference

12 December 2020

Fetuin-A adsorption and stabilization of calcium carbonate nanoparticles in a simulated body fluid

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F6809703

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1155/2016/6809703

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547766%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547766%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

27547766

2 references