Clinical Development of the E75 Vaccine in Breast Cancer (Q26745440)

The HER2 Receptor in Breast Cancer: Pathophysiology, Clinical Use, and New Advances in Therapy

Europe PubMed Central

title

Clinical Development of the E75 Vaccine in Breast Cancer (English)

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Guy T Clifton

1

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Victor Gall

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2

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George E Peoples

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3

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Elizabeth A Mittendorf

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4

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language of work or name

English

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publication date

April 2016

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published in

Breast Care

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volume

11

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issue

2

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page(s)

116-21

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cites work

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HER-2 pulsed dendritic cell vaccine can eliminate HER-2 expression and impact ductal carcinoma in situ.

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28 September 2017

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28 September 2017

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28 September 2017

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HER-2/neu-specific monoclonal antibodies collaborate with HER-2/neu-targeted granulocyte macrophage colony-stimulating factor secreting whole cell vaccination to augment CD8+ T cell effector function and tumor-free survival in Her-2/neu-transgenic m

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28 November 2018

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28 November 2018

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Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER-2 peptide E75 (369-377) combined with granulocyte macrophage colony-stimulating factor in HLA-A2+ patients with metastatic breast and ovarian cancer.

28 November 2018

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HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice.

28 November 2018

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28 November 2018

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28 November 2018

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Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients

28 November 2018

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12 December 2020

Peptide priming of cytolytic activity to HER-2 epitope 369-377 in healthy individuals

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12 December 2020

Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity

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12 December 2020

Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines

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12 December 2020

Axillary lymph node cellular immune response to HER-2/neu peptides in patients with carcinoma of the breast

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12 December 2020

Augmented HER-2 specific immunity during treatment with trastuzumab and chemotherapy

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12 December 2020

Changes in an HER-2 peptide upregulating HLA-A2 expression affect both conformational epitopes and CTL recognition: implications for optimization of antigen presentation and tumor-specific CTL induction

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12 December 2020

Vaccination with a HER2/neu peptide induces intra- and inter-antigenic epitope spreading in patients with early stage breast cancer

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12 December 2020