Diversity of Intestinal Macrophages in Inflammatory Bowel Diseases (Q26772342)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

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6

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page(s)

613

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cites work

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Revisiting Crohn's disease as a primary immunodeficiency of macrophages

7 April 2017

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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

7 April 2017

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Tissue-resident macrophages

7 April 2017

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Alternative activation of macrophages

7 April 2017

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

7 April 2017

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Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration

7 April 2017

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IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis

7 April 2017

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Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

7 April 2017

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The chemokine system in diverse forms of macrophage activation and polarization

7 April 2017

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Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

7 April 2017

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Lamina propria macrophage phenotypes in relation to Escherichia coli in Crohn's disease.

28 September 2017

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Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation

28 September 2017

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Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD.

28 September 2017

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Hallmarks of epithelial to mesenchymal transition are detectable in Crohn's disease associated intestinal fibrosis

28 September 2017

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A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1.

28 September 2017

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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

28 September 2017

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Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages

28 September 2017

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Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

28 September 2017

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Macrophage polarisation: an immunohistochemical approach for identifying M1 and M2 macrophages.

28 September 2017

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M2 macrophages activate WNT signaling pathway in epithelial cells: relevance in ulcerative colitis

28 September 2017

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Lesional accumulation of CD163-expressing cells in the gut of patients with inflammatory bowel disease.

28 September 2017

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Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense

28 September 2017

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IL-13 promotes collagen accumulation in Crohn's disease fibrosis by down-regulation of fibroblast MMP synthesis: a role for innate lymphoid cells?

28 September 2017

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Macrophage plasticity and polarization in tissue repair and remodelling

28 September 2017

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Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

28 September 2017

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28 September 2017

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Hck is a key regulator of gene expression in alternatively activated human monocytes

28 September 2017

1 reference

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The role of retinoic acid in tolerance and immunity

28 September 2017

1 reference

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Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

28 September 2017

1 reference

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Macrophages: master regulators of inflammation and fibrosis

28 September 2017

1 reference

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Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation

28 September 2017

1 reference

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Delayed resolution of acute inflammation in ulcerative colitis is associated with elevated cytokine release downstream of TLR4.

28 September 2017

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Selective and specific macrophage ablation is detrimental to wound healing in mice

28 September 2017

1 reference

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Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

28 September 2017

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Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

28 September 2017

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Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells

28 September 2017

1 reference

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The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria

28 September 2017

1 reference

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Power of genetic association studies in the presence of linkage disequilibrium and allelic heterogeneity.

28 September 2017

1 reference

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Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis

28 September 2017

1 reference

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Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5

28 September 2017

1 reference

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TREM-1--expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases

28 September 2017

1 reference

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The C-type lectin-like domain superfamily

28 September 2017

1 reference

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The macrophage scavenger receptor CD163.

28 September 2017

1 reference

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Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

CD163: a specific marker of macrophages in paraffin-embedded tissue samples

28 September 2017

1 reference

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Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease

28 September 2017

1 reference

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Medical therapy for Crohn's disease strictures

28 September 2017

1 reference

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Crohn's disease and the NOD2 gene: a role for paneth cells

28 September 2017

1 reference

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Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli

28 September 2017

2 references

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28 September 2017

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

7 January 2021

inferred from DOI database lookup

Macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Paradoxically increased FOXP3+ T cells in IBD do not preferentially express the isoform of FOXP3 lacking exon 2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Isolation and phenotypic characterization of colonic macrophages

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

An analysis of the reliability of detection and diagnostic value of various pathological features in Crohn's disease and ulcerative colitis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Microgranulomas in grossly normal rectal mucosa in Crohn's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

31 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Adipokines from local fat cells shape the macrophage compartment of the creeping fat in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

CD14(hi)HLA-DR(dim) macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Colon mucosa of patients both with spondyloarthritis and Crohn's disease is enriched with macrophages expressing the scavenger receptor CD163.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

The V249I polymorphism of the CX3CR1 gene is associated with fibrostenotic disease behavior in patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00613

Soluble CD163: a marker molecule for monocyte/macrophage activity in disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670857

Increased number of FoxP3+CD4+ regulatory T cells in inflammatory bowel disease

28 November 2018

1 reference

12 December 2020

Differential distribution of B7.1 (CD80) and B7.2 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD)

1 reference

12 December 2020

Macrophages expressing triggering receptor expressed on myeloid cells-1 are underrepresented in the human intestine

1 reference

12 December 2020

Soluble CD163, a Specific Macrophage Activation Marker, is Decreased by Anti-TNF-αAntibody Treatment in Active Inflammatory Bowel Disease

1 reference

12 December 2020

Submucosal fibrosis and basic-fibroblast growth factor-positive neutrophils correlate with colonic stenosis in cases of ulcerative colitis

1 reference

12 December 2020

Investigating the role of proinflammatory CD16+ monocytes in the pathogenesis of inflammatory bowel disease

1 reference

12 December 2020

Evidence for a CD14+ population of monocytes in inflammatory bowel disease mucosa--implications for pathogenesis

1 reference

12 December 2020

Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells

1 reference

12 December 2020

Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2015.00613

1 reference

1 reference

1 reference

PubMed publication ID

26697009

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