Lipid Raft-Mediated Regulation of Hyaluronan-CD44 Interactions in Inflammation and Cancer (Q26782792)

Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase

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Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB

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CD44 in rheumatoid arthritis

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Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators

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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

7 April 2017

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HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity

7 April 2017

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Purification, cloning, and expression of human plasma hyaluronidase

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Cholesterol lowering: role in cancer prevention and treatment

7 April 2017

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Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction

7 April 2017

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Functional rafts in cell membranes

7 April 2017

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Lipid rafts and signal transduction

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Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility

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Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae

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Molecular cloning and functional expression of the rat 175-kDa hyaluronan receptor for endocytosis

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Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

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Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

7 April 2017

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

7 April 2017

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The extracellular matrix: a dynamic niche in cancer progression

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Lipid rafts as a membrane-organizing principle

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Structure and function of sphingolipid- and cholesterol-rich membrane rafts

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7 April 2017

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GPI-anchored proteins do not reside in ordered domains in the live cell plasma membrane

7 April 2017

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Hyaluronan breakdown contributes to immune defense against group A Streptococcus

28 September 2017

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CD147: regulator of hyaluronan signaling in invasiveness and chemoresistance

28 September 2017

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Specific sizes of hyaluronan oligosaccharides stimulate fibroblast migration and excisional wound repair

28 September 2017

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A novel mechanism of regulating breast cancer cell migration via palmitoylation-dependent alterations in the lipid raft affiliation of CD44.

28 September 2017

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Membrane rafts as a novel target in cancer therapy.

28 September 2017

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Low molecular weight hyaluronan activates cytosolic phospholipase A2α and eicosanoid production in monocytes and macrophages.

28 September 2017

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Cooperativity of CD44 and CD49d in leukemia cell homing, migration, and survival offers a means for therapeutic attack

28 September 2017

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CD44 receptor unfolding enhances binding by freeing basic amino acids to contact carbohydrate ligand

28 September 2017

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Human milk hyaluronan enhances innate defense of the intestinal epithelium

28 September 2017

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CD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness

28 September 2017

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High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat.

28 September 2017

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Membrane cholesterol modulates the hyaluronan-binding ability of CD44 in T lymphocytes and controls rolling under shear flow.

28 September 2017

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Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts

28 September 2017

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The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans

28 September 2017

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Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity.

28 September 2017

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The high and low molecular weight forms of hyaluronan have distinct effects on CD44 clustering

28 September 2017

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Specific-sized hyaluronan fragments promote expression of human β-defensin 2 in intestinal epithelium

28 September 2017

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The role of lipid rafts in cancer cell adhesion and migration

28 September 2017

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Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling

28 September 2017

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Fragmented hyaluronan is an autocrine chemokinetic motility factor supported by the HAS2-HYAL2/CD44 system on the plasma membrane

28 September 2017

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28 September 2017

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Cell-surface receptor for complement component C1q (gC1qR) is a key regulator for lamellipodia formation and cancer metastasis

28 September 2017

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Differential use of chondroitin sulfate to regulate hyaluronan binding by receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages.

28 September 2017

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CD44 in hematological neoplasias

28 September 2017

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28 September 2017

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Low cholesterol triggers membrane microdomain-dependent CD44 shedding and suppresses tumor cell migration.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS.

28 September 2017

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Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides

28 September 2017

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28 September 2017

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Rheostatic signaling by CD44 and hyaluronan

28 September 2017

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ADAM function in embryogenesis

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CD44 engagement promotes matrix-derived survival through the CD44-SRC-integrin axis in lipid rafts

28 September 2017

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28 September 2017

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Extracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronan

28 September 2017

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Lipid rafts and membrane traffic

28 September 2017

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Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells

28 September 2017

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Hyaluronan synthesis induces microvillus-like cell surface protrusions

28 September 2017

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Hyaluronidases: their genomics, structures, and mechanisms of action

28 September 2017

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Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10.

28 September 2017

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Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44

28 September 2017

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Shedding light on ADAM metalloproteinases

28 September 2017

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Threat matrix: low-molecular-weight hyaluronan (HA) as a danger signal

28 September 2017

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Hyaluronan fragments induce endothelial cell differentiation in a CD44- and CXCL1/GRO1-dependent manner

28 September 2017

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Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.

28 September 2017

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CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase.

28 September 2017

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Hyaluronan catabolism: a new metabolic pathway

28 September 2017

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Hyaluronan: from extracellular glue to pericellular cue.

28 September 2017

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CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

28 September 2017

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Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration.

28 September 2017

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Devising a pathway for hyaluronan catabolism: are we there yet?

28 September 2017

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Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses

28 September 2017

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Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway

28 September 2017

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Role of sulfation in CD44-mediated hyaluronan binding induced by inflammatory mediators in human CD14(+) peripheral blood monocytes

28 September 2017

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Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization

28 September 2017

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Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration

28 September 2017

1 reference

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Epidermal growth factor activates hyaluronan synthase 2 in epidermal keratinocytes and increases pericellular and intracellular hyaluronan

28 September 2017

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Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival

28 September 2017

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Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton

28 September 2017

1 reference

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Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate

28 September 2017

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Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding.

28 September 2017

1 reference

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Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronan

28 September 2017

1 reference

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Hyaluronan: its nature, distribution, functions and turnover

28 September 2017

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Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.

28 September 2017

1 reference

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CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma.

28 September 2017

1 reference

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CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway

28 September 2017

1 reference

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CD44 and its interaction with extracellular matrix.

28 September 2017

1 reference

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Glycosylation of CD44 negatively regulates its recognition of hyaluronan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Lipid sorting in epithelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Secondary and tertiary structures of hyaluronan in aqueous solution, investigated by rotary shadowing-electron microscopy and computer simulation. Hyaluronan is a very efficient network-forming polymer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Determination of synovial fluid hyaluronate concentration and polymerisation by high performance liquid chromatography

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Differential activation of ERK and Rac mediates the proliferative and anti-proliferative effects of hyaluronan and CD44.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

EGF induces coalescence of different lipid rafts

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

CD44: structure, function, and association with the malignant process.

31 May 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

31 May 2018

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

The distributions and diffusivities of small ions in chondroitin sulphate, hyaluronate and some proteoglycan solutions.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Hyaluronidase-sensitive halos around adherent cells. Their role in blocking lymphocyte-mediated cytolysis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells

31 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Targeting hyaluronan interactions in malignant gliomas and their drug-resistant multipotent progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Hyaluronan fragments stimulate endothelial recognition of injury through TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Hyaluronan-oligosaccharide-induced transcription of metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility [published erratum appears in J Cell Biol 1992 Aug;118(3):753]

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Auditory feedback in learning and maintenance of vocal behaviour.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Transforming growth factor-beta induces CD44 cleavage that promotes migration of MDA-MB-435s cells through the up-regulation of membrane type 1-matrix metalloproteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Hyaluronan binding identifies the most proliferative activated and memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Transient GPI-anchored protein homodimers are units for raft organization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4542320

Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer

28 November 2018

1 reference

12 December 2020

Requirement for CD44 in activated T cell extravasation into an inflammatory site

1 reference

12 December 2020

Tumor-associated hyaluronic acid: a new sensitive and specific urine marker for bladder cancer

1 reference

12 December 2020

TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44

1 reference

12 December 2020

TNF-alpha induction of CD44-mediated leukocyte adhesion by sulfation

1 reference

12 December 2020

Stromal and epithelial expression of tumor markers hyaluronic acid and HYAL1 hyaluronidase in prostate cancer

1 reference

12 December 2020

Hyaluronate in vasculogenesis

1 reference

12 December 2020

Oligosaccharides of hyaluronan are potent activators of dendritic cells

1 reference

12 December 2020

BCA-1 (CXCL13) and SLC (CCL21) production and lymphoid neogenesis in rheumatoid synovitis.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00420

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.3389/FIMMU.2015.00420

1 reference

1 reference

1 reference

PubMed publication ID

26347743

1 reference