The gut microbiota and host health: a new clinical frontier (Q26785649)

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20 October 2020

The gut microbiota and host health: a new clinical frontier (English)

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David Adams

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Francesca Fava

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Gideon M. Hirschfield

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Georgina L. Hold

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James M. Kinross

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Hauke Smidt

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Kieran Tuohy

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23 February 2020

Linda V Thomas

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Ailsa Hart

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author name string

Gerben D A Hermes

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23 February 2020

Mohammed Nabil Quraishi

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Erwin G Zoetendal

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publication date

2 September 2015

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1 February 2016

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20 October 2020

4 references

20 June 2019

16 September 2019

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20 October 2020

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page(s)

330-339

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issue

2

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Creative Commons Attribution-NonCommercial

23 February 2020

copyright license

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Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk

1 reference

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Fecal Microbiome and Volatile Organic Compound Metabolome in Obese Humans With Nonalcoholic Fatty Liver Disease

7 April 2017

1 reference

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Linking long-term dietary patterns with gut microbial enterotypes

7 April 2017

1 reference

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Enteric dysbiosis associated with a mouse model of alcoholic liver disease

7 April 2017

1 reference

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

7 April 2017

1 reference

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Liver autoimmunity triggered by microbial activation of natural killer T cells

7 April 2017

1 reference

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Accuracy of body mass index in diagnosing obesity in the adult general population

7 April 2017

1 reference

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Obesity alters gut microbial ecology

7 April 2017

1 reference

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Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine

7 April 2017

1 reference

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Microbial ecology: human gut microbes associated with obesity

7 April 2017

1 reference

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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

7 April 2017

1 reference

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Fat, fibre and cancer risk in African Americans and rural Africans

7 April 2017

1 reference

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Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

7 April 2017

1 reference

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Minireview: Gut microbiota: the neglected endocrine organ

7 April 2017

1 reference

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A metagenomic insight into our gut's microbiome

7 April 2017

1 reference

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Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

7 April 2017

1 reference

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Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics

7 April 2017

1 reference

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Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

7 April 2017

1 reference

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Diet rapidly and reproducibly alters the human gut microbiome

7 April 2017

1 reference

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A metagenome-wide association study of gut microbiota in type 2 diabetes

7 April 2017

1 reference

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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

7 April 2017

1 reference

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Richness of human gut microbiome correlates with metabolic markers

7 April 2017

1 reference

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Gut microbiota composition correlates with diet and health in the elderly

7 April 2017

1 reference

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Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome

7 April 2017

1 reference

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Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans

7 April 2017

1 reference

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Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach

7 April 2017

1 reference

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Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial

7 April 2017

1 reference

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Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis

28 September 2017

1 reference

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Disease-specific alterations in the enteric virome in inflammatory bowel disease

28 September 2017

1 reference

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The mucosa-associated microbiota of PSC patients is characterized by low diversity and low abundance of uncultured Clostridiales II.

28 September 2017

1 reference

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Fecal microbiota transplantation as therapy for inflammatory bowel disease: a systematic review and meta-analysis.

28 September 2017

1 reference

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Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway

28 September 2017

1 reference

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Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect

28 September 2017

1 reference

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Molecular ecological tools to decipher the role of our microbial mass in obesity

28 September 2017

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The first 1000 cultured species of the human gastrointestinal microbiota.

28 September 2017

1 reference

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Oral probiotic VSL#3 attenuates the circulatory disturbances of patients with cirrhosis and ascites.

28 September 2017

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Analysis of the intestinal lumen microbiota in an animal model of colorectal cancer

28 September 2017

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Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?

28 September 2017

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Co-occurrence of anaerobic bacteria in colorectal carcinomas.

28 September 2017

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Dominant fecal microbiota in newly diagnosed untreated inflammatory bowel disease patients

28 September 2017

1 reference

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Effects of probiotics on nonalcoholic fatty liver disease: a meta-analysis.

28 September 2017

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Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

28 September 2017

1 reference

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Dietary intervention impact on gut microbial gene richness

28 September 2017

1 reference

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Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin

28 September 2017

1 reference

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Colonic mucosa-associated diffusely adherent afaC+ Escherichia coli expressing lpfA and pks are increased in inflammatory bowel disease and colon cancer.

28 September 2017

1 reference

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Dysbiosis signature of fecal microbiota in colorectal cancer patients

28 September 2017

1 reference

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Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

28 September 2017

1 reference

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Gut metagenome in European women with normal, impaired and diabetic glucose control

28 September 2017

1 reference

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Pleiotropic roles of bile acids in metabolism

28 September 2017

1 reference

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Some are more equal than others: the role of "keystone" species in the degradation of recalcitrant substrates

28 September 2017

1 reference

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Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology

28 September 2017

1 reference

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Microbial pathways in colonic sulfur metabolism and links with health and disease

28 September 2017

1 reference

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Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease

28 September 2017

1 reference

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Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice.

28 September 2017

1 reference

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Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management

28 September 2017

1 reference

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The role of the gut microbiota in nutrition and health.

28 September 2017

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The keystone-pathogen hypothesis.

28 September 2017

1 reference

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Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome.

28 September 2017

1 reference

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Intestinal inflammation targets cancer-inducing activity of the microbiota.

28 September 2017

1 reference

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Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

28 September 2017

1 reference

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Bacterial translocation and changes in the intestinal microbiome associated with alcoholic liver disease

28 September 2017

1 reference

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The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

28 September 2017

1 reference

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Relevance of protein fermentation to gut health

28 September 2017

1 reference

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Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics

28 September 2017

1 reference

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Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitis

28 September 2017

1 reference

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Probiotics in hepatology.

28 September 2017

1 reference

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Towards the human colorectal cancer microbiome

28 September 2017

1 reference

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High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas

28 September 2017

1 reference

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Contribution of gut bacteria to liver pathobiology

28 September 2017

1 reference

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Treatment of relapsing mild-to-moderate ulcerative colitis with the probiotic VSL#3 as adjunctive to a standard pharmaceutical treatment: a double-blind, randomized, placebo-controlled study.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

E. coli-mediated gut inflammation in genetically predisposed Crohn's disease patients

28 September 2017

1 reference

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The distinction of metabolically 'healthy' from 'unhealthy' obese individuals

28 September 2017

1 reference

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Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease.

28 September 2017

1 reference

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Human colonic microbiota associated with diet, obesity and weight loss

28 September 2017

1 reference

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Mechanisms of action of probiotics: recent advances

28 September 2017

1 reference

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Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases

28 September 2017

1 reference

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Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis

28 September 2017

1 reference

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Immunology of the gut and liver: a love/hate relationship.

28 September 2017

1 reference

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Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Diet-derived phenols in plasma and tissues and their implications for health

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Role of the microbiota and antibiotics in primary sclerosing cholangitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

The itinerary of Streptococcus gallolyticus infection in patients with colonic malignant disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Perspective: alpha-bugs, their microbial partners, and the link to colon cancer

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Experimental portal fibrosis produced by intraportal injection of killed nonpathogenic Escherichia coli in rabbits

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Decline in presumptively protective gut bacterial species and metabolites are paradoxically associated with disease improvement in pediatric Crohn's disease during enteral nutrition.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Colonization of the human gut by E. coli and colorectal cancer risk

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Effect of probiotics on inducing remission and maintaining therapy in ulcerative colitis, Crohn's disease, and pouchitis: meta-analysis of randomized controlled trials

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Low counts of Faecalibacterium prausnitzii in colitis microbiota.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Long-term treatment of primary sclerosing cholangitis in children with oral vancomycin: an immunomodulating antibiotic

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Intestinal permeability and bacterial growth of the small bowel in patients with primary sclerosing cholangitis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752653

Alteration of local microflora and α-defensins hyper-production in colonic adenoma mucosa

28 November 2018

1 reference

12 December 2020

Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial

1 reference

12 December 2020

The gut-adherent microbiota of PSC-IBD is distinct to that of IBD.

1 reference

12 December 2020

Hepatic steatosis after intestinal bypass--prevention and reversal by metronidazole, irrespective of protein-calorie malnutrition

1 reference

12 December 2020

Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection

1 reference

12 December 2020

10.1136/GUTJNL-2015-309990

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338727%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338727%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338727%20AND%20SRC:MED&resulttype=core&format=json