A Review: The Current In Vivo Models for the Discovery and Utility of New Anti-leishmanial Drugs Targeting Cutaneous Leishmaniasis (Q26786195)

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1 June 2020

George E. Johnson

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Farrokh Modabber

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1 June 2020

Robert Don

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PLoS Neglected Tropical Diseases

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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Leishmania tropica: Pathogenicity and in vitro macrophage function in strains of inbred mice

31 May 2018

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31 May 2018

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31 May 2018

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Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation

31 May 2018

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The histopathological and immunological pattern of CBA mice infected with Leishmania amazonensis after treatment with pyrazole carbohydrazide derivatives.

21 January 2018

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Immunological and pathological evaluation of rhesus macaques infected with Leishmania major

21 January 2018

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21 January 2018

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Leishmania tropica experimental infection in the rat using luciferase-transfected parasites.

21 January 2018

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21 January 2018

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Preliminary study towards a novel experimental model to study localized cutaneous leishmaniasis caused by Leishmania (Leishmania) mexicana

21 January 2018

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Competition between two steinernematid nematode species for an insect host at different soil depths

21 January 2018

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Resolution of an infection with Leishmania braziliensis confers complete protection to a subsequent challenge with Leishmania major in BALB/c mice.

21 January 2018

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Golden hamster (Mesocricetus auratus) as an experimental model for Leishmania (Viannia) braziliensis infection.

21 January 2018

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In situ characterization of the granulomatous immune response with time in nonhealing lesional skin of Leishmania braziliensis-infected rhesus macaques (Macaca mulatta).

21 January 2018

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The site of cutaneous infection influences the immunological response and clinical outcome of hamsters infected with Leishmania panamensis.

21 January 2018

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Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice.

21 January 2018

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Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes.

21 January 2018

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The Pathogenesis of Leishmania aethiopica Infection in BALB/c Mice

21 January 2018

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21 January 2018

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Colorimetric assay for screening compounds against Leishmania amastigotes grown in macrophages.

28 November 2018

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Lack of general immunosuppression during visceral Leishmania tropica infection in BALB/c mice: augmented antibody response to thymus-independent antigens and polyclonal activation

28 November 2018

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Metastatic capability of Leishmania (Viannia) panamensis and Leishmania (Viannia) guyanensis in golden hamsters.

28 November 2018

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28 November 2018

Cutaneous leishmaniasis

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12 December 2020

Experimental infection with Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the marmoset, Callithrix penicillata (Primates:Callithricidae)

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12 December 2020

Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models

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12 December 2020

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12 December 2020

Clonal diversity in the expression and stability of the metastatic capability of Leishmania guyanensis in the golden hamster

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12 December 2020

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12 December 2020

Effectiveness of Allopurinol against Leishmania Braziliensis Panamensis in Aotus Trivirgatus

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12 December 2020

Canine American cutaneous leishmaniasis: a clinical and immunological study in dogs naturally infected with Leishmania braziliensis braziliensis in an endemic area of Rio de Janeiro, Brazil

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Systemic and compartmentalised immune responses in a Leishmania braziliensis-macaque model of self-healing cutaneous leishmaniasis

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Green fluorescent protein (GFP): applications in cell-based assays for drug discovery

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12 December 2020

Allopurinol ribonucleoside as an antileishmanial agent. Biological effects, metabolism, and enzymatic phosphorylation

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12 December 2020

Study of the safety, immunogenicity and efficacy of attenuated and killed Leishmania (Leishmania) major vaccines in a rhesus monkey (Macaca mulatta) model of the human disease

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12 December 2020

Leishmania amazonensis: the Asian rhesus macaques (Macaca mulatta) as an experimental model for study of cutaneous leishmaniasis

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12 December 2020

Leishmania major: effect of infectious dose on T cell subset development in BALB/c mice

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12 December 2020

A comparative study of susceptibility of inbred and outbred mouse strains compared with hamsters to infection with New World cutaneous leishmaniases

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12 December 2020

Evaluating the efficacy of allopurinol for the treatment of cutaneous leishmaniasis

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10.1371/JOURNAL.PNTD.0003889

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26334763%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26334763%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26334763%20AND%20SRC:MED&resulttype=core&format=json