Pharmacological and Combined Interventions to Reduce Vaccine Injection Pain in Children and Adults: Systematic Review and Meta-Analysis (Q26800959)

26201016

meta-analysis

1 reference

26201016

title

Pharmacological and Combined Interventions to Reduce Vaccine Injection Pain in Children and Adults: Systematic Review and Meta-Analysis (English)

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20 June 2019

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19 September 2019

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12 September 2020

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Rebecca Pillai Riddell

6

Rebecca Pillai Riddell

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Christine T. Chambers

Christine T Chambers

7

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Scott A Halperin

4

Scott A Halperin

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Anna Taddio

2

Anna Taddio

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author name string

Vibhuti Shah

1

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C Meghan McMurtry

3

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Melanie Noel

The Clinical Journal of Pain

5

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language of work or name

English

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publication date

October 2015

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1 October 2015

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20 June 2019

25 June 2019

22 July 2019

19 September 2019

12 September 2020

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20 June 2019

25 June 2019

22 July 2019

19 September 2019

12 September 2020

31

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issue

10 Suppl

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page(s)

S38-63

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copyright license

Creative Commons Attribution-NonCommercial-NoDerivatives

5 references

20 June 2019

25 June 2019

22 July 2019

19 September 2019

12 September 2020

Methodology for Knowledge Synthesis of the Management of Vaccination Pain and Needle Fear

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7 April 2017

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7 April 2017

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Breastfeeding or breast milk for procedural pain in neonates

7 April 2017

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Estimating the mean and variance from the median, range, and the size of a sample

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Systematic review of observational (behavioral) measures of pain for children and adolescents aged 3 to 18 years

7 April 2017

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Systematic review of the psychometric properties, interpretability and feasibility of self-report pain intensity measures for use in clinical trials in children and adolescents

7 April 2017

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28 September 2017

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Effects of prophylactic and therapeutic paracetamol treatment during vaccination on hepatitis B antibody levels in adults: two open-label, randomized controlled trials

28 September 2017

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Breastfeeding and pain relief in full-term neonates during immunization injections: a clinical randomized trial.

28 September 2017

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Evaluation of methods to relieve parental perceptions of vaccine-associated pain and anxiety in children: a pilot study

28 September 2017

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Immunization site pain: case definition and guidelines for collection, analysis, and presentation of immunization safety data

28 September 2017

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Effective analgesia using physical interventions for infant immunizations

28 September 2017

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A double-blind randomised controlled trial of 25% oral glucose for pain relief in 2-month old infants undergoing immunisation

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Addressing parental concerns about pain during childhood vaccination: is there enough time to include pain management in the ambulatory setting?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Nonnutritive sucking and oral sucrose relieve neonatal pain during intramuscular injection of hepatitis vaccine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Skin-to-skin contact and/or oral 25% dextrose for procedural pain relief for term newborn infants.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials.

28 September 2017

1 reference

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Effectiveness and tolerability of pharmacologic and combined interventions for reducing injection pain during routine childhood immunizations: systematic review and meta-analyses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

A randomized controlled trial of vapocoolant for pediatric immunization distress relief

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Oral sucrose and a pacifier for pain relief during simple procedures in preterm infants: a randomized controlled trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Effect of breast-feeding on pain relief during infant immunization injections

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Pain reduction during pediatric immunizations: evidence-based review and recommendations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

The use of breast-feeding for pain relief during neonatal immunization injections.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Immunogenicity and adverse reactions of influenza vaccination in elderly patients given acetaminophen or placebo

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Topical vapocoolant quickly and effectively reduces vaccine-associated pain: results of a randomized, single-blinded, placebo-controlled study.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Mechanisms of sucrose and non-nutritive sucking in procedural pain management in infants

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

A randomized double-blind, placebo-controlled trial of the EMLA patch for the reduction of pain associated with intramuscular injection in four to six-year-old children

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Randomised controlled trial of sucrose by mouth for the relief of infant crying after immunisation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Effects of acetaminophen on adverse effects of influenza vaccination in health care workers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Ice freezes pain? A review of the clinical effectiveness of analgesic cold therapy

28 September 2017

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Vaccine immune response and side effects with the use of acetaminophen with influenza vaccine

28 September 2017

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Child/adolescent behavioral and emotional problems: implications of cross-informant correlations for situational specificity

28 September 2017

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From the mouth of babes: Getting vaccinated doesn't have to hurt

28 September 2017

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Comparison of analgesic effect of direct breastfeeding, oral 25% dextrose solution and placebo during 1st DPT vaccination in healthy term infants: a randomized, placebo controlled trial

31 May 2018

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Efficacy of parental application of eutectic mixture of local anesthetics for intravenous insertion.

31 May 2018

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Vapocoolant spray is equally effective as EMLA cream in reducing immunization pain in school-aged children.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Topical ibuprofen for skin analgesia prior to venepuncture.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

The use of a topical refrigerant anesthetic to reduce injection pain in children.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Use of lidocaine-prilocaine cream for vaccination pain in infants.

31 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Antimicrobial activity of local anesthetics: lidocaine and procaine.

31 May 2018

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Effect of lidocaine-prilocaine cream on pain from subcutaneous injection

31 May 2018

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A comparison of the antibacterial properties of six local analgesic agents.

31 May 2018

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Antibacterial Properties of Lidocaine

31 May 2018

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Comparison of EMLA cream with rattles on reducing immunization pain in four months infants.

31 May 2018

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28 November 2018

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28 November 2018

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EMLA(R) cream: a pain-relieving strategy for childhood vaccination

28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Interventions to reduce pain during vaccination in infancy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Sucrose decreases infant biobehavioral pain response to immunizations: a randomized controlled trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Stress at three-month immunization: parents' and infants' salivary cortisol response in relation to the use of pacifier and oral glucose

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Analgesic properties of oral sucrose during routine immunizations at 2 and 4 months of age.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Routine immunization practices: use of topical anesthetics and oral analgesics.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Topical 4% amethocaine gel reduces the pain of subcutaneous measles-mumps-rubella vaccination

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

EMLA cream and oral glucose for immunization pain in 3-month-old infants

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Effects of chewing gum on responses to routine painful procedures in children

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Fear of injections in young adults: prevalence and associations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vacci

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Intra-oral administration of sweet-tasting substances and infants' crying response to immunization: a randomized, placebo-controlled trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Lidocaine-prilocaine patch decreases the pain associated with the subcutaneous administration of measles-mumps-rubella vaccine but does not adversely affect the antibody response.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

No negative influence of EMLA application prior to BCG vaccination.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

A eutectic mixture of lidocaine and prilocaine for alleviating vaccination pain in infants.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

[The EMLA cream versus placebo in MMR vaccination of older children in general practice]

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Home application of EMLA cream prior to venipuncture. Is it feasible in pediatric ENT day care surgery?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Minimizing pain associated with prekindergarten intramuscular injections.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Local anaesthetics as antimicrobial agents: structure-action considerations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4900424

Sucrose as an analgesic agent for infants during immunization injections

28 November 2018

1 reference

12 December 2020

Suckling- and sucrose-induced analgesia in human newborns

1 reference

12 December 2020

Mother as shield: differential effects of contact and nursing on pain responsivity in infant rats--evidence for nonopioid mediation

1 reference

12 December 2020

Effects of a skin refrigerant/anesthetic and age on the pain responses of infants receiving immunizations

1 reference

12 December 2020

"Sucrose analgesia" and diphtheria-tetanus-pertussis immunizations at 2 and 4 months

1 reference

12 December 2020

Oral glucose as an analgesic to reduce infant distress following immunization at the age of 3, 5 and 12 months

1 reference

12 December 2020

Effect of oral sucrose on pain during DPT immunization in older infants

1 reference

12 December 2020

Milk-induced hypoalgesia in human newborns

1 reference

12 December 2020

Role of breastfeeding in pain response during injectable immunisation among infants

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12 December 2020

The effects of a pacifying stimulus on behavioral and adrenocortical responses to circumcision in the newborn

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12 December 2020

10.1097/AJP.0000000000000281

Identifiers

DOI

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Fatcat ID

release_gml46qjydzhhjfzgggn5toceyy

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PMC publication ID

4900424

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