The Complex Role of STAT3 in Viral Infections (Q26801053)

23 March 2019

20 November 2019

28 November 2019

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22 December 2019

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STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

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The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor

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Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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RANTES and MIP-1alpha activate stats in T cells

7 April 2017

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

7 April 2017

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

7 April 2017

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Crystal structure of unphosphorylated STAT3 core fragment

7 April 2017

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Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation

7 April 2017

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Somatic STAT3 mutations in large granular lymphocytic leukemia

7 April 2017

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How cells respond to interferons

7 April 2017

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

7 April 2017

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Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?

7 April 2017

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Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells

7 April 2017

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Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia

7 April 2017

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Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer

7 April 2017

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The multifunctional NS1 protein of influenza A viruses

7 April 2017

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Regulation of cytokine signaling pathways by PIAS proteins

7 April 2017

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Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling

7 April 2017

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

7 April 2017

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STATs in cancer inflammation and immunity: a leading role for STAT3

7 April 2017

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Stats: transcriptional control and biological impact

7 April 2017

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Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

7 April 2017

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Reduced phosphorylation of Stat3 at Ser-727 mediated by casein kinase 2 - protein phosphatase 2A enhances Stat3 Tyr-705 induced tumorigenic potential of glioma cells

28 September 2017

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Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.

28 September 2017

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STAT3 regulates proliferation and survival of CD8+ T cells: enhances effector responses to HSV-1 infection, and inhibits IL-10+ regulatory CD8+ T cells in autoimmune uveitis

28 September 2017

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Human metapneumovirus inhibits the IL-6-induced JAK/STAT3 signalling cascade in airway epithelium.

28 September 2017

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Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus.

28 September 2017

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HCMV activates the IL-6-JAK-STAT3 axis in HepG2 cells and primary human hepatocytes

28 September 2017

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28 September 2017

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Innate immunity to H5N1 influenza viruses in humans

28 September 2017

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Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing

28 September 2017

1 reference

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Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

28 September 2017

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Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.

28 September 2017

1 reference

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Role and regulation of STAT3 phosphorylation at Ser727 in melanocytes and melanoma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Dynamics and non-canonical aspects of JAK/STAT signalling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of Class O Forkhead transcription factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT3 signaling: anticancer strategies and challenges.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdelta

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Extracellular hepatitis C virus core protein activates STAT3 in human monocytes/macrophages/dendritic cells via an IL-6 autocrine pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT3 activation induced by Epstein-Barr virus latent membrane protein1 causes vascular endothelial growth factor expression and cellular invasiveness via JAK3 And ERK signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell lymphoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Canonical and non-canonical JAK-STAT signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

T40214/PEI complex: a potent therapeutics for prostate cancer that targets STAT3 signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

JAK-STAT signaling: from interferons to cytokines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Persistent activation of STAT3 by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT3 as a central mediator of neoplastic cellular transformation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Interleukin-10 suppression of myeloid cell activation--a continuing puzzle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Inhibitors of cytokine signal transduction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT protein interference and suppression of cytokine signal transduction by measles virus V protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Epstein-Barr virus regulates STAT1 through latent membrane protein 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Essential role of STAT3 for embryonic stem cell pluripotency

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Nucleocytoplasmic shuttling of persistently activated STAT3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Tyrosine dephosphorylation of STAT3 in SARS coronavirus-infected Vero E6 cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496485

STAT signaling is active during early mammalian development.

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

IL-5 and granulocyte-macrophage colony-stimulating factor activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

STAT3 negatively regulates type I IFN-mediated antiviral response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Aberrant inflammation and lethality to septic peritonitis in mice lacking STAT3 in macrophages and neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

General nature of the STAT3-activated anti-inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Human immunodeficiency virus type 1 (HIV-1) Nef activates STAT3 in primary human monocyte/macrophages through the release of soluble factors: involvement of Nef domains interacting with the cell endocytotic machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F272359

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

21 January 2018

1 reference

12 December 2020

Activation of signal transducer and activator of transcription-3 (Stat3) expression by interferon-gamma and interleukin-6 in hepatoma cells

1 reference

12 December 2020

Steel factor induces serine phosphorylation of Stat3 in human growth factor-dependent myeloid cell lines

1 reference

12 December 2020

A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory

1 reference

12 December 2020

STAT3 expression in salivary gland tumours

1 reference

12 December 2020

Identifiers

DOI

10.1155/2015/272359

1 reference

221620

221620

1 reference

1 reference

1 reference